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TTC21A Knockout Cell Lines

Gene: TTC21A

Official Full Name: tetratricopeptide repeat domain 21Aprovided by HGNC

Gene Summary: Involved in flagellated sperm motility and spermatid development. Predicted to be located in cilium. Predicted to be part of intraciliary transport particle A. Implicated in spermatogenic failure 37. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO21319 TTC21A Knockout cell line (HeLa) Human TTC21A 1:3~1:6 Negative Online Inquiry
KO21320 TTC21A Knockout cell line (HCT 116) Human TTC21A 1:2~1:4 Negative Online Inquiry
KO21321 TTC21A Knockout cell line (A549) Human TTC21A 1:3~1:4 Negative Online Inquiry

Background

TTC21A Gene Knockout Cell Lines are advanced biological models specifically engineered to investigate the functional role of the TTC21A gene in cellular processes. Through the use of CRISPR-Cas9 or other gene-editing technologies, these cell lines effectively silence the expression of the TTC21A gene, allowing researchers to examine the implications of its absence on cell behavior, signaling pathways, and phenotype variations. By providing a controlled environment where the effects of the knocked-out gene can be observed, these cell lines serve as a powerful tool for elucidating gene function and cellular dynamics.

The key functionality of TTC21A Gene Knockout Cell Lines lies in their ability to reveal insights into the processes of cilia formation and maintenance, as TTC21A is integral to cilia-related signaling pathways. These pathways are crucial in numerous biological functions, including developmental processes and cellular responsiveness to external stimuli. The gene knockout model enables researchers to study a range of related disorders, including ciliopathies and certain types of cancer, facilitating a comprehensive understanding of the underlying molecular mechanisms.

In terms of scientific importance, TTC21A Gene Knockout Cell Lines are invaluable in both research and clinical settings. They pave the way for drug discovery, biomarker identification, and the exploration of therapeutic targets related to ciliary function. Their relevance extends to areas such as developmental biology, genetics, and pharmacology, making them a versatile asset in the laboratory.

What sets our TTC21A Gene Knockout Cell Lines apart from alternatives is their robust validation process and user-friendly protocols. Each line is thoroughly characterized in terms of gene expression levels and functional assays, ensuring reproducibility and reliability in research outcomes. Furthermore, we offer comprehensive support and technical guidance to users, enhancing their experimentation experience.

For researchers and clinicians, the ability to readily access specialized knockout models like TTC21A can significantly streamline study designs and contribute to meaningful scientific advances. Our commitment to quality and innovation is backed by years of expertise in developing biological products aimed at facilitating groundbreaking research. Choose our TTC21A Gene Knockout Cell Lines and empower your investigations with exceptional tools that contribute to the future of biomedical science.

Please note that all services are for research use only. Not intended for any clinical use.

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