Gene: TTC12
Official Full Name: tetratricopeptide repeat domain 12provided by HGNC
Gene Summary: Involved in axonemal dynein complex assembly and sperm axoneme assembly. Located in centrosome and cytoplasm. Implicated in acute lymphoblastic leukemia; alcohol dependence; drug dependence (multiple); nicotine dependence; and primary ciliary dyskinesia 45. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO20349 | TTC12 Knockout cell line (HeLa) | Human | TTC12 | 1:3~1:6 | Negative | Online Inquiry |
KO20350 | TTC12 Knockout cell line (HCT 116) | Human | TTC12 | 1:2~1:4 | Negative | Online Inquiry |
KO20351 | TTC12 Knockout cell line (HEK293) | Human | TTC12 | 1:3~1:6 | Negative | Online Inquiry |
KO20352 | TTC12 Knockout cell line (A549) | Human | TTC12 | 1:3~1:4 | Negative | Online Inquiry |
TTC12 Gene Knockout Cell Lines are genetically engineered cell models designed to help researchers investigate the functional role of the TTC12 gene. This gene is implicated in various cellular processes, including signal transduction and gene regulation. By creating knockout cell lines where the TTC12 gene is specifically ablated, scientists can study the resultant phenotypic changes, enhancing our understanding of its biological significance.
The key function of these cell lines lies in their ability to facilitate the exploration of gene function and its pathway interactions in controlled environments. Researchers can employ these knockout models to examine alterations in cellular behaviors such as proliferation, migration, and apoptosis, providing insights into how the loss of TTC12 affects critical cellular functions and disease mechanisms.
The scientific importance of TTC12 Gene Knockout Cell Lines extends to their applications in both basic research and clinical settings. They serve as valuable tools for the study of genetic disorders associated with dysregulated pathways that involve TTC12, leading to potential therapeutic targets. Furthermore, these models are crucial for drug discovery processes, allowing for the evaluation of pharmacological interventions aimed at restoring normal function in TTC12-related pathways.
One of the distinct advantages of using TTC12 Gene Knockout Cell Lines is their specificity; they provide a high-fidelity model that other gene-editing methods often lack. This specificity minimizes off-target effects and enhances the reliability of experimental outcomes, making them a superior choice for researchers looking for precision in genetic studies.
For researchers and clinicians, the value of TTC12 Gene Knockout Cell Lines is underscored by their ability to deepen our understanding of gene function and disease mechanisms, ultimately paving the way for more targeted therapies. They offer an advanced research platform that promises to accelerate discoveries in genetics and molecular biology.
Our company specializes in developing high-quality, reliable biological products tailored for research needs, ensuring that scientists have access to the best tools for their investigations. With our expertise in gene knockout technology, we are committed to supporting groundbreaking research initiatives that push the boundaries of scientific knowledge.
Please note that all services are for research use only. Not intended for any clinical use.
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