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TRIM16L Knockout Cell Lines

Gene: TRIM16L

Official Full Name: tripartite motif containing 16 like (pseudogene)provided by HGNC

Gene Summary: Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO23839 TRIM16L Knockout cell line (HeLa) Human TRIM16L 1:3~1:6 Negative Online Inquiry
KO23840 TRIM16L Knockout cell line (HCT 116) Human TRIM16L 1:2~1:4 Negative Online Inquiry
KO23841 TRIM16L Knockout cell line (HEK293) Human TRIM16L 1:3~1:6 Negative Online Inquiry
KO23842 TRIM16L Knockout cell line (A549) Human TRIM16L 1:3~1:4 Negative Online Inquiry

Background

TRIM16L Gene Knockout Cell Lines are specifically engineered cellular models designed to study the functional implications of the TRIM16L gene, which is implicated in various biological processes, including immune regulation and response to cellular stress. These cell lines have undergone targeted gene disruption, offering scientists a unique tool to elucidate the downstream effects of TRIM16L deficiency on cellular behavior and signaling.

The key mechanism by which TRIM16L functions involves its role as an E3 ubiquitin ligase, contributing to ubiquitin-mediated protein degradation pathways. By employing these knockout cell lines, researchers can dissect the pathways affected by the loss of TRIM16L, enhancing our understanding of its contribution to critical physiological functions. This is particularly vital in the context of diseases where TRIM16L expression is altered, such as cancer and autoimmune disorders.

In terms of scientific importance, TRIM16L Gene Knockout Cell Lines have extensive applications in basic research and preclinical studies. They serve as powerful models to explore cellular responses to cytokines, stressors, and other stimuli, thereby providing insight into potential therapeutic targets. Additionally, they can facilitate drug discovery efforts by enabling high-throughput screening of compounds aimed at modulating TRIM16L-related pathways.

What sets our TRIM16L Gene Knockout Cell Lines apart from alternative models is their rigorous validation and optimization. Produced under stringent quality control conditions, these cell lines have been characterized for specific phenotypic and genomic alterations that allow researchers to trust the fidelity of their findings. Furthermore, our commitment to customer support ensures that researchers receive guidance on experimental design and troubleshooting.

The availability of TRIM16L Gene Knockout Cell Lines presents a valuable opportunity for researchers and clinicians focusing on the intricacies of gene function and disease mechanisms. By investing in our unique product offering, you will gain access to cutting-edge tools backed by our extensive expertise in biological products and cell line development. This empowers your research efforts and aids in unlocking new avenues for therapeutic intervention, ultimately contributing to advances in health and medicine.

Please note that all services are for research use only. Not intended for any clinical use.

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