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TRIM10 Knockout Cell Lines

Gene: TRIM10

Official Full Name: tripartite motif containing 10provided by HGNC

Gene Summary: The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to cytoplasmic bodies. Studies in mice suggest that this protein plays a role in terminal differentiation of erythroid cells. Alternate splicing of this gene generates two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO32284 TRIM10 Knockout cell line (HCT 116) Human TRIM10 1:2~1:4 Negative Online Inquiry

Background

TRIM10 Gene Knockout Cell Lines are specialized cellular models that have been genetically engineered to disable the TRIM10 gene, which is implicated in various pathways related to immune regulation, cellular signaling, and oncogenesis. By utilizing CRISPR-Cas9 technology, these cell lines allow researchers to explore the functional implications of TRIM10 loss-of-function in a controlled environment, facilitating detailed investigations into its role in health and disease.

The primary function of TRIM10 Gene Knockout Cell Lines is to serve as a tool for elucidating the biological mechanisms associated with the TRIM10 protein, including its involvement in ubiquitination processes that regulate protein stability and cellular responses. The knockout of the TRIM10 gene creates a novel experimental platform for studying the effects of this protein's absence on cellular behavior, such as proliferation, apoptosis, and inflammatory responses, thereby enhancing our understanding of its contributions to various pathologies.

Scientifically, these cell lines are crucial for advancing research in cancer biology, autoimmunity, and infectious diseases, enabling the development of targeted therapeutic strategies. Their use in preclinical studies may lead to significant breakthroughs in understanding disease mechanisms and therapeutic interventions.

Compared to alternatives, such as transient knockdown methods that may lead to variable results, TRIM10 Gene Knockout Cell Lines offer stable and reproducible gene editing that ensures consistent experimental outcomes. This reliability makes them an invaluable asset for high-throughput screenings and functional assays.

Researchers and clinicians will find these cell lines particularly beneficial due to their ability to mimic in vivo conditions, providing insights that are directly applicable to human health. The availability of TRIM10 Gene Knockout Cell Lines can empower scientific advancements, leading to better diagnostic markers and therapeutic targets.

Our company prides itself on its commitment to excellence in biogenetic engineering, offering high-quality products that cater to the needs of researchers in academia and industry alike. By leveraging our expertise, we ensure that our TRIM10 Gene Knockout Cell Lines are meticulously validated and ready for immediate application in innovative research endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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