Gene: TRAPPC6A
Official Full Name: trafficking protein particle complex subunit 6Aprovided by HGNC
Gene Summary: This gene encodes a component of the trafficking protein particle complex, which tethers transport vesicles to the cis-Golgi membrane. Loss of expression of the related gene in mouse affects coat and eye pigmentation, suggesting that the encoded protein may be involved in melanosome biogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO13079 | TRAPPC6A Knockout cell line (HeLa) | Human | TRAPPC6A | 1:3~1:6 | Negative | Online Inquiry |
KO13080 | TRAPPC6A Knockout cell line (HCT 116) | Human | TRAPPC6A | 1:2~1:4 | Negative | Online Inquiry |
KO13081 | TRAPPC6A Knockout cell line (HEK293) | Human | TRAPPC6A | 1:3~1:6 | Negative | Online Inquiry |
KO13082 | TRAPPC6A Knockout cell line (A549) | Human | TRAPPC6A | 1:3~1:4 | Negative | Online Inquiry |
TRAPPC6A Gene Knockout Cell Lines are specialized cellular systems engineered to eliminate the expression of the TRAPPC6A gene, which plays a crucial role in intracellular transport and Golgi apparatus maintenance. By utilizing the CRISPR-Cas9 genome editing technology, these cell lines provide a reliable model for studying the functional consequences of TRAPPC6A deficiency in various biological processes.
The primary function of TRAPPC6A involves regulating membrane trafficking and protein secretion, which are essential for maintaining cellular homeostasis and function. These knockout cell lines allow researchers to dissect the molecular pathways affected by loss of TRAPPC6A, offering insights into diseases linked to dysfunctional vesicle transport, such as neurodegenerative disorders and certain cancers.
In the realm of research and clinical studies, TRAPPC6A Gene Knockout Cell Lines are invaluable tools for understanding disease mechanisms at a cellular level. They are particularly useful for drug discovery and validation, allowing researchers to screen for therapeutics that target pathways affected by TRAPPC6A disruption. Additionally, these cell lines serve as a basis for investigating potential gene therapy approaches, facilitating the development of novel treatment strategies for patients with conditions resulting from TRAPPC6A mutations.
What sets our TRAPPC6A Gene Knockout Cell Lines apart is their rigorously validated genotypic and phenotypic profiles, ensuring consistency and reliability in experimental outcomes. Unlike alternative cell line models, ours offer enhanced specificity for TRAPPC6A studies, backed by comprehensive support documentation and robust technical assistance.
Researchers and clinicians can greatly benefit from these cell lines, as they not only streamline experimental workflows but also contribute to accelerated insights into fundamental biological processes and therapeutic solutions. Our commitment to excellence in biological products, combined with years of experience in cell line development, positions us as a leader in providing innovative tools that advance scientific discovery.
Please note that all services are for research use only. Not intended for any clinical use.
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