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TPRKB Knockout Cell Lines

Gene: TPRKB

Official Full Name: TP53RK binding proteinprovided by HGNC

Gene Summary: Enables protein kinase binding activity. Involved in tRNA threonylcarbamoyladenosine modification. Located in cytosol and nucleus. Part of EKC/KEOPS complex. Implicated in Galloway-Mowat syndrome 5. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO23212 TPRKB Knockout cell line (HeLa) Human TPRKB 1:3~1:6 Negative Online Inquiry
KO23213 TPRKB Knockout cell line (HCT 116) Human TPRKB 1:2~1:4 Negative Online Inquiry
KO23214 TPRKB Knockout cell line (HEK293) Human TPRKB 1:3~1:6 Negative Online Inquiry

Background

TPRKB Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to lack the TPRKB gene, which plays a crucial role in various biological processes, including mitotic regulation and cellular response to stress. These knockout cells are generated using advanced CRISPR/Cas9 technology, allowing precise modifications in the genomic DNA to facilitate studies on gene function, signaling pathways, and cellular mechanisms.

The key mechanism behind TPRKB knockout involves the elimination of the gene itself, leading to functional impairment of related cellular pathways. This functional deficiency enables researchers to explore the effects on cell proliferation, apoptosis, and differentiation, thereby shedding light on the roles played by TPRKB in both normal physiological processes and disease models such as cancer or neurodegenerative disorders.

In the research and clinical context, TPRKB Gene Knockout Cell Lines serve as invaluable tools for drug discovery and development. They provide a platform for screening and validating therapeutic targets, thereby accelerating the path from bench to bedside. Moreover, understanding TPRKB's function could unveil novel strategies for the treatment of diseases characterized by aberrant cell cycle regulation or stress responses.

What sets our TPRKB Gene Knockout Cell Lines apart from other genetic models is not only their specificity and precision but also their comprehensive characterization, ensuring reliability in experimental outcomes. They have been validated across multiple assays, making them a trustworthy resource for researchers aiming for reproducibility in their studies.

For researchers, clinicians, and biotech developers, utilizing TPRKB Gene Knockout Cell Lines allows for greater insights into therapeutic innovations and biological discoveries, significantly enhancing the potential for breakthroughs in various fields of biology and medicine. Our company stands out as a leader in the development of high-quality, genetically modified cell lines, offering robust support and expertise to facilitate your research objectives.

Please note that all services are for research use only. Not intended for any clinical use.

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