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TOMM7 Knockout Cell Lines

Gene: TOMM7

Official Full Name: translocase of outer mitochondrial membrane 7provided by HGNC

Gene Summary: This gene encodes a subunit of the translocase of the outer mitochondrial membrane. The encoded protein regulates the assembly and stability of the translocase complex. [provided by RefSeq, Oct 2012]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO05978 TOMM7 Knockout cell line (HeLa) Human TOMM7 1:3~1:6 Negative Online Inquiry
KO05979 TOMM7 Knockout cell line (HCT 116) Human TOMM7 1:2~1:4 Negative Online Inquiry
KO05980 TOMM7 Knockout cell line (HEK293) Human TOMM7 1:3~1:6 Negative Online Inquiry
KO05981 TOMM7 Knockout cell line (A549) Human TOMM7 1:3~1:4 Negative Online Inquiry

Background

TOMM7 Gene Knockout Cell Lines are specially engineered cellular models designed to facilitate the study of the TOMM7 gene, which encodes for a crucial component of the mitochondrial translocase of the outer membrane (TOM) complex. These cell lines have been developed through precise CRISPR-Cas9 gene editing techniques, effectively knocking out the TOMM7 gene to create a model that can be utilized to investigate the implications of TOMM7 deficiency in various biological processes, including mitochondrial function and cellular metabolism.

The key function of TOMM7 is to aid in the import of mitochondrial proteins essential for organelle biogenesis and function. By eliminating TOMM7 expression, researchers can investigate crucial pathways associated with mitochondrial dynamics, apoptosis, and energy metabolism, providing valuable insights into conditions such as neurodegenerative diseases, metabolic syndromes, and cancer. This gene knockout model enables the dissection of the molecular and cellular consequences of TOMM7 loss, making it an indispensable tool for basic research and therapeutic development.

In comparison to alternative models, TOMM7 Gene Knockout Cell Lines offer superior specificity and reproducibility due to the precision of CRISPR technology. Researchers benefit from a reliable platform that allows for detailed functional assays without the confounding effects present in other knockdown approaches, thus ensuring robust experimental outcomes.

This product is particularly valuable for academic researchers and pharmaceutical companies looking to explore mitochondrial biology or develop innovative treatments targeting mitochondrial dysfunction. By providing a model that accurately represents the effects of TOMM7 loss, scientists can accelerate their discoveries in a field that holds significant therapeutic potential.

Our company prides itself on its commitment to advancing scientific research by delivering high-quality genetic tools. Our expertise in genetic engineering and cellular biology ensures that our TOMM7 Gene Knockout Cell Lines are meticulously developed to meet the needs of researchers striving to understand complex biological systems.

Please note that all services are for research use only. Not intended for any clinical use.

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