Gene: TNPO2
Official Full Name: transportin 2provided by HGNC
Gene Summary: Predicted to enable nuclear import signal receptor activity and nuclear localization sequence binding activity. Predicted to be involved in protein import into nucleus. Predicted to act upstream of or within negative regulation of muscle cell differentiation. Predicted to be active in cytoplasm and nucleus. Implicated in intellectual developmental disorder with hypotonia, impaired speech, and dysmorphic facies. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO26830 | TNPO2 Knockout cell line (HeLa) | Human | TNPO2 | 1:3~1:6 | Negative | Online Inquiry |
KO26831 | TNPO2 Knockout cell line (HCT 116) | Human | TNPO2 | 1:2~1:4 | Negative | Online Inquiry |
KO26832 | TNPO2 Knockout cell line (HEK293) | Human | TNPO2 | 1:3~1:6 | Negative | Online Inquiry |
KO26833 | TNPO2 Knockout cell line (A549) | Human | TNPO2 | 1:3~1:4 | Negative | Online Inquiry |
TNPO2 Gene Knockout Cell Lines are specialized cellular models created by targeted gene editing techniques to eliminate the expression of the TNPO2 gene, which encodes a protein involved in nucleocytoplasmic transport and has implications in various biological processes such as viral infection and cellular signaling. These knockout cell lines serve as indispensable tools for researchers aiming to investigate the role of TNPO2 in cellular functions and disease mechanisms.
The primary function of TNPO2 is to mediate the transport of proteins across the nuclear pore complex, influencing a variety of oncogenic pathways and potentially contributing to tumorigenesis. By knocking out TNPO2, researchers can elucidate the pathways influenced by this protein, assess the cellular response to stress, and explore the interactions between TNPO2 and pathogen-derived proteins, particularly in understanding viral pathogenesis.
The scientific importance of TNPO2 Gene Knockout Cell Lines lies in their application across various research fields, including cancer biology, virology, and molecular genetics. Their use can lead to novel discoveries about gene function, protein interactions, and therapeutic targets, offering valuable insights for both basic research and clinical applications.
Compared to traditional cell lines, TNPO2 Gene Knockout Cell Lines present specific advantages, including enhanced specificity in studying gene function and the potential to produce more relevant data when simulating human disease states. Furthermore, these cell lines are developed through cutting-edge CRISPR/Cas9 technology, ensuring precise and efficient gene disruption, which draws interest from researchers looking for reliable models.
For researchers, clinicians, and pharmaceutical companies, the TNPO2 Gene Knockout Cell Lines represent a crucial resource for advancing scientific knowledge and therapeutic development. Their ability to replicate disease-specific conditions allows for a deeper understanding of potential treatments and biomarker discovery.
Our company is committed to providing high-quality biological research tools, backed by extensive expertise in genetic engineering and cell biology, ensuring that our products support innovative research and contribute to breakthroughs in biomedical science.
Please note that all services are for research use only. Not intended for any clinical use.
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