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TNKS1BP1 Knockout Cell Lines

Gene: TNKS1BP1

Official Full Name: tankyrase 1 binding protein 1provided by HGNC

Gene Summary: Enables ankyrin repeat binding activity and enzyme binding activity. Involved in cellular response to ionizing radiation; double-strand break repair; and positive regulation of protein phosphorylation. Located in several cellular components, including adherens junction; heterochromatin; and nucleus. Part of CCR4-NOT complex. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO02670 TNKS1BP1 Knockout cell line (HeLa) Human TNKS1BP1 1:3~1:6 Negative Online Inquiry
KO02671 TNKS1BP1 Knockout cell line (HCT 116) Human TNKS1BP1 1:2~1:4 Negative Online Inquiry
KO02672 TNKS1BP1 Knockout cell line (HEK293) Human TNKS1BP1 1:3~1:6 Negative Online Inquiry
KO02673 TNKS1BP1 Knockout cell line (A549) Human TNKS1BP1 1:3~1:4 Negative Online Inquiry

Background

TNKS1BP1 Gene Knockout Cell Lines represent a pioneering advancement in the field of genetic research, specifically targeting the TNKS1BP1 gene, which encodes for a crucial protein involved in various cellular processes, including DNA repair and regulation of cell proliferation. These genetically modified cell lines are created using cutting-edge CRISPR/Cas9 gene-editing technology, allowing for precise deletion of the TNKS1BP1 gene, thereby enabling scientists to explore the protein’s role in signaling pathways and disease mechanisms.

The key function of TNKS1BP1 knockout cell lines is their ability to facilitate the study of the gene's contributions to critical biological processes and disease states, such as cancer and neurodegenerative disorders. By observing the resultant phenotypic changes when the TNKS1BP1 gene is absent, researchers can elucidate its role in cellular stress responses and therapeutic resistance. This mechanistic understanding can lead to the identification of novel biomarkers and therapeutic targets.

The scientific importance of these knockout cell lines lies in their vast applications in basic and translational research. They serve as invaluable tools in drug discovery, allowing researchers to test the efficacy of potential compounds in a controlled setting where the specific genetic factor is absent. Additionally, they can be utilized to model diseases in vitro, contributing to a greater understanding of pathophysiological mechanisms and potential therapeutic interventions.

Compared to other gene knockout models, the TNKS1BP1 Gene Knockout Cell Lines provide distinct advantages, including higher efficiency of gene disruption and reduced off-target effects associated with CRISPR technology. This specificity enhances the reliability of experimental results, making them more applicable to therapeutic development.

For researchers and clinicians, the value of TNKS1BP1 Gene Knockout Cell Lines is underscored by their ability to drive innovative research outcomes and facilitate breakthroughs in understanding complex biological systems. These cell lines empower scientists to probe deeper into cell biology and influence future therapeutic strategies.

Our company prides itself on its expertise in providing high-quality biological products and cell lines that meet rigorous scientific standards, ensuring that researchers have access to the essential tools needed to advance their work and drive impactful discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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