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TMSB15C Knockout Cell Lines

Gene: TMSB15C

Official Full Name: thymosin beta 15Cprovided by HGNC

Gene Summary: Predicted to enable actin monomer binding activity. Involved in positive regulation of cell migration. Predicted to be located in cytoskeleton. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO13154 TMSB15C Knockout cell line (HeLa) Human TMSB15C 1:3~1:6 Negative Online Inquiry
KO13155 TMSB15C Knockout cell line (HCT 116) Human TMSB15C 1:2~1:4 Negative Online Inquiry
KO13156 TMSB15C Knockout cell line (HEK293) Human TMSB15C 1:3~1:6 Negative Online Inquiry
KO13157 TMSB15C Knockout cell line (A549) Human TMSB15C 1:3~1:4 Negative Online Inquiry

Background

TMSB15C Gene Knockout Cell Lines are engineered cellular systems where the TMSB15C gene has been selectively inactivated. This gene encodes a cytoskeletal protein, thymosin beta-15, which plays a pivotal role in actin dynamics and cellular motility. The engineered knockout lines provide invaluable tools for studying the functional implications of TMSB15C in various biological processes, such as cell migration, proliferation, and apoptosis.

The core mechanism of action for these knockout cell lines lies in the complete absence of TMSB15C, allowing researchers to study how the loss of this protein affects cellular behaviors and signaling pathways. Researchers can conduct comparative studies with wild-type cells to assess differences in cytoskeletal organization and response to external stimuli. This knockout model is crucial for dissecting the contributions of TMSB15C to both normal physiology and disease states, including cancer and other pathologies where cell motility is a factor.

In scientific research and clinical settings, TMSB15C Gene Knockout Cell Lines serve as a powerful experimental platform for validating drug targets, uncovering disease mechanisms, and screening for novel therapeutic agents. The ability to manipulate the genetic expression of specific proteins opens new avenues for investigating therapeutic interventions in a more targeted and precise manner.

Compared to alternative models, such as transient knockdowns or overexpressers, these stable knockout lines provide a robust and reproducible system for long-term studies, minimizing variability inherent in other methods. Additionally, the knockout design enables researchers to maintain physiological relevance, bypassing artifacts that could arise from incomplete silencing of gene expression.

For researchers and clinicians focused on understanding cell behavior in health and disease, TMSB15C Gene Knockout Cell Lines represent a critical resource that can propel their findings forward. The insights gained from using these unique cell lines can lead to breakthroughs in therapy design and enhance knowledge of cellular mechanisms.

Our company specializes in the advanced production of genetically modified cell lines, underpinned by years of expertise in molecular biology and biotherapeutic research. We are committed to delivering high-quality biological tools that empower scientists to achieve their research goals efficiently and effectively.

Please note that all services are for research use only. Not intended for any clinical use.

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