Gene: TMEM50A
Official Full Name: transmembrane protein 50Aprovided by HGNC
Gene Summary: This gene is located in the RH gene locus, between the RHD and RHCE genes. The function of its protein product is unknown; however, its sequence has potential transmembrane domains suggesting that it may be an integral membrane protein. Its position between the RH genes suggests that polymorphisms in this gene may be tightly linked to RH haplotypes and may contribute to selective pressure for or against certain RH haplotypes. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO29114 | TMEM50A Knockout cell line (HeLa) | Human | TMEM50A | 1:3~1:6 | Negative | Online Inquiry |
KO29115 | TMEM50A Knockout cell line (HCT 116) | Human | TMEM50A | 1:2~1:4 | Negative | Online Inquiry |
KO29116 | TMEM50A Knockout cell line (HEK293) | Human | TMEM50A | 1:3~1:6 | Negative | Online Inquiry |
KO29117 | TMEM50A Knockout cell line (A549) | Human | TMEM50A | 1:3~1:4 | Negative | Online Inquiry |
TMEM50A Gene Knockout Cell Lines are a specialized set of genetically modified cell lines engineered to lack the TMEM50A gene, which encodes a protein involved in various cellular processes including membrane dynamics and intracellular signaling. These cell lines serve as invaluable tools for researchers investigating the physiological roles of TMEM50A and its implications in disease mechanisms, particularly in cancer and neurodegenerative disorders. The knockout mechanism relies on CRISPR-Cas9 technology for precise deletion or disruption of the TMEM50A gene, providing a robust approach to studying gene function and its downstream effects on cellular behavior.
These cell lines showcase distinct functionalities, including altered cell proliferation, apoptosis, and signaling pathways, enabling scientists to dissect the molecular networks influenced by TMEM50A. Their use in research not only helps elucidate the gene's role in normal physiology but also contributes to understanding its potential as a therapeutic target for various conditions. In clinical settings, the insights gained from TMEM50A knockout cells can lead to developments in gene therapy and personalized medicine strategies by identifying biomarkers associated with treatment responsiveness.
Compared to traditional methods of gene manipulation, TMEM50A Gene Knockout Cell Lines offer enhanced specificity, reproducibility, and ease of use, significantly reducing the time and resources required for experimental validation. Their unique ability to simulate the absence of this gene allows for more accurate modeling of disease states, thus offering researchers a powerful avenue for exploratory studies.
In conclusion, our expertise in genetic engineering and commitment to providing high-quality biological products makes TMEM50A Gene Knockout Cell Lines an essential resource for researchers and clinicians seeking to advance their understanding of genetic regulation and its impact on human health. We pride ourselves on supporting groundbreaking research with reliable tools that foster scientific innovation.
Please note that all services are for research use only. Not intended for any clinical use.
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