Gene: TMEM259
Official Full Name: transmembrane protein 259provided by HGNC
Gene Summary: Predicted to be involved in positive regulation of ERAD pathway and response to endoplasmic reticulum stress. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO03903 | TMEM259 Knockout cell line (HeLa) | Human | TMEM259 | 1:3~1:6 | Negative | Online Inquiry |
KO03904 | TMEM259 Knockout cell line (HCT 116) | Human | TMEM259 | 1:2~1:4 | Negative | Online Inquiry |
KO03905 | TMEM259 Knockout cell line (HEK293) | Human | TMEM259 | 1:3~1:6 | Negative | Online Inquiry |
KO03906 | TMEM259 Knockout cell line (A549) | Human | TMEM259 | 1:3~1:4 | Negative | Online Inquiry |
TMEM259 Gene Knockout Cell Lines are genetically engineered models specifically created to investigate the role of the TMEM259 gene in various biological processes. These cell lines utilize CRISPR-Cas9 technology to achieve precise knockout of the TMEM259 gene, enabling researchers to explore its function in cellular signaling, immune responses, and disease mechanisms. The absence of TMEM259 in these models allows for the assessment of alterations in cellular behavior, thereby providing insights into the gene's involvement in pathologies such as autoimmune disorders and cancers.
The primary mechanism by which these knockout cell lines function is through the disruption of the TMEM259 protein, believed to be involved in modulating immune signaling pathways. By studying the resulting phenotypic and molecular changes, researchers can elucidate the physiological role of TMEM259 and identify potential therapeutic targets. These cell lines serve as invaluable tools in drug development, biomarker discovery, and functional genomics, supporting advancements in personalized medicine and tailored treatments.
The scientific importance of TMEM259 Gene Knockout Cell Lines is underscored by their versatility in research and clinical applications. Compared to traditional knockout models, our cell lines offer enhanced ease of use, reproducibility, and scalability, which are critical for high-throughput screening assays. Additionally, the precision of CRISPR editing minimizes off-target effects, ensuring reliable experimental outcomes.
For researchers and clinicians aiming to deepen their understanding of TMEM259’s role in health and disease, our knockout cell lines represent a superior choice. They facilitate systematic studies that can lead to groundbreaking discoveries and meaningful advancements in therapeutic strategies.
Our company prides itself on its commitment to providing high-quality biological products and cutting-edge solutions that cater to the evolving needs of the scientific community. With expertise in gene editing and cellular biology, we ensure that our products not only drive innovation but also contribute significantly to the advancement of scientific research.
Please note that all services are for research use only. Not intended for any clinical use.
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