Gene: TIAL1
Official Full Name: TIA1 cytotoxic granule associated RNA binding protein like 1provided by HGNC
Gene Summary: The protein encoded by this gene is a member of a family of RNA-binding proteins, has three RNA recognition motifs (RRMs), and binds adenine and uridine-rich elements in mRNA and pre-mRNAs of a wide range of genes. It regulates various activities including translational control, splicing and apoptosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The different isoforms have been show to function differently with respect to post-transcriptional silencing. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO20892 | TIAL1 Knockout cell line (HeLa) | Human | TIAL1 | 1:3~1:6 | Negative | Online Inquiry |
KO20893 | TIAL1 Knockout cell line (HCT 116) | Human | TIAL1 | 1:2~1:4 | Negative | Online Inquiry |
KO20894 | TIAL1 Knockout cell line (HEK293) | Human | TIAL1 | 1:3~1:6 | Negative | Online Inquiry |
KO20895 | TIAL1 Knockout cell line (A549) | Human | TIAL1 | 1:3~1:4 | Negative | Online Inquiry |
TIAL1 Gene Knockout Cell Lines are highly specialized cellular models developed to study the function of the TIAL1 gene, which encodes for a critical RNA-binding protein involved in the regulation of various cellular processes, including gene expression, RNA splicing, and stability. These knockout lines are generated through advanced CRISPR-Cas9 technology, allowing for precise deletion of the TIAL1 gene, providing researchers with an efficient tool to investigate its role in cellular pathways and disease mechanisms.
The primary function of TIAL1 Gene Knockout Cell Lines lies in their ability to elucidate the impact of TIAL1 deletion on cellular physiology. By studying the resultant phenotypes, researchers can assess the gene's influence on various processes, such as cell proliferation, apoptosis, and response to stress. Importantly, these cell lines serve as invaluable assets in cancer research, neurological studies, and investigations into autoimmune disorders, contributing to a better understanding of the pathophysiology and potential therapeutic targets.
One significant advantage of TIAL1 Gene Knockout Cell Lines over alternative models is the specificity and validity associated with gene editing via the CRISPR-Cas9 system, which minimizes off-target effects, leading to more reliable experimental outcomes. Additionally, these cell lines can be cultivated in a variety of standard tissue culture conditions, making them accessible for routine laboratory use without the need for extensive optimization processes.
For researchers and clinicians, utilizing TIAL1 Gene Knockout Cell Lines can accelerate the discovery of novel molecular pathways and therapeutic interventions, providing insights that are critical for advancing precision medicine. Our company, with its commitment to cutting-edge biotechnological advancements and rigorous quality control, is proud to offer these specialized cell lines, empowering the scientific community to explore the complexities of gene function and their implications in health and disease.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.