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TDRP Knockout Cell Lines

Gene: TDRP

Official Full Name: testis development related proteinprovided by HGNC

Gene Summary: Acts upstream of or within spermatogenesis. Located in cytosol and nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO13492 TDRP Knockout cell line (HEK293) Human TDRP 1:3~1:6 Negative Online Inquiry
KO13493 TDRP Knockout cell line (A549) Human TDRP 1:3~1:4 Negative Online Inquiry

Background

TDRP Gene Knockout Cell Lines are genetically modified cellular models created through targeted gene disruption techniques, specifically designed to investigate the function and role of the TDRP (Testis Development-Related Protein) gene in various biological processes. These cell lines enable researchers to study the phenotypic and functional consequences that result from the absence of TDRP, providing a powerful platform for understanding its implications in development, reproduction, and related pathologies.

The primary mechanism by which TDRP Gene Knockout Cell Lines operate involves the precise editing of the TDRP gene through techniques such as CRISPR-Cas9 or homologous recombination, leading to the complete ablation of gene expression. This allows for the detailed examination of resultant cellular behaviors, signaling pathways, and interactions with other biomolecules, yielding insights that contribute to our understanding of spermatogenesis and potentially male infertility.

The scientific importance of these knockout cell lines lies in their applications across various fields, including reproductive biology, genetics, and therapeutic research. They serve as invaluable tools for elucidating TDRP's multifaceted role in cellular differentiation and development, forming the foundation for novel treatments targeting reproductive disorders or cancers.

Compared to alternative models, such as wild-type cell lines or less precise gene-editing methods, TDRP Gene Knockout Cell Lines provide unparalleled specificity and reliability. Their rigorous validation ensures that researchers can trust the results generated, reducing variability and improving reproducibility.

For researchers and clinicians, these knockout cell lines hold immense value, enabling the exploration of previously uncharted pathways and facilitating the development of innovative therapeutic strategies. By providing insights that were otherwise inaccessible, they can lead to breakthroughs in understanding and treating reproductive challenges.

Our company, with its extensive expertise in genetic engineering and cell line development, is committed to delivering high-quality, reliable biological products like the TDRP Gene Knockout Cell Lines. We strive to support the research community with advanced tools that push the frontiers of biomedical understanding and therapeutic potential.

Please note that all services are for research use only. Not intended for any clinical use.

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