Gene: TCEANC2
Official Full Name: transcription elongation factor A N-terminal and central domain containing 2provided by HGNC
Gene Summary: Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO27059 | TCEANC2 Knockout cell line (HeLa) | Human | TCEANC2 | 1:3~1:6 | Negative | Online Inquiry |
KO27060 | TCEANC2 Knockout cell line (HCT 116) | Human | TCEANC2 | 1:2~1:4 | Negative | Online Inquiry |
KO27061 | TCEANC2 Knockout cell line (HEK293) | Human | TCEANC2 | 1:3~1:6 | Negative | Online Inquiry |
KO27062 | TCEANC2 Knockout cell line (A549) | Human | TCEANC2 | 1:3~1:4 | Negative | Online Inquiry |
TCEANC2 gene knockout cell lines are specially designed cellular models in which the TCEANC2 gene has been inactivated or "knocked out." This targeted genetic modification serves as a powerful tool for researchers examining the functional roles of TCEANC2 in various biological processes and disease mechanisms. By eliminating the expression of this gene, scientists can study the resulting phenotypic changes, providing insights into gene function, regulatory networks, and potential therapeutic targets.
The mechanistic approach to using TCEANC2 knockout cell lines involves sophisticated gene editing techniques, such as CRISPR/Cas9 or TALENs, which enable precise alterations to the genome. Once the TCEANC2 gene is disrupted, researchers can perform comparative analyses between knockout and wild-type cell lines to elucidate the gene's contributions to cellular pathways. This methodology not only facilitates the understanding of disease pathways but also helps in identifying potential biomarkers and drug targets relevant to cancer, metabolic diseases, and neurodegenerative disorders.
The scientific importance of TCEANC2 knockout cell lines extends to both research and clinical applications. In a research context, they provide a platform for high-throughput screening of compounds that may influence or rescue the phenotypes associated with TCEANC2 loss. Clinically, the insights gained from these models can accelerate drug discovery and development processes by pinpointing critical molecular interactions necessary in targeted therapies.
What differentiates TCEANC2 knockout cell lines from alternative models is their specificity and precision. Other models may offer broader observations but can entail confounding effects due to the presence of functional alleles. The complete inactivation of TCEANC2 allows for more accurate interpretations of cellular responses and a clearer understanding of the gene's role in human health and disease.
For researchers and clinicians alike, the TCEANC2 gene knockout cell lines represent a valuable asset that drives innovation in molecular biology and therapeutic discovery. Our company, backed by extensive expertise in genetic engineering and cellular research, is dedicated to providing high-quality biological products like these to advance scientific exploration and development.
Please note that all services are for research use only. Not intended for any clinical use.
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