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TASP1 Knockout Cell Lines

Gene: TASP1

Official Full Name: taspase 1provided by HGNC

Gene Summary: This gene encodes an endopeptidase that cleaves specific substrates following aspartate residues. The encoded protein undergoes posttranslational autoproteolytic processing to generate alpha and beta subunits, which reassemble into the active alpha2-beta2 heterotetramer. It is required to cleave MLL, a protein required for the maintenance of HOX gene expression, and TFIIA, a basal transcription factor. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO13563 TASP1 Knockout cell line (HeLa) Human TASP1 1:3~1:6 Negative Online Inquiry
KO13564 TASP1 Knockout cell line (HCT 116) Human TASP1 1:2~1:4 Negative Online Inquiry
KO13565 TASP1 Knockout cell line (HEK293) Human TASP1 1:3~1:6 Negative Online Inquiry
KO13566 TASP1 Knockout cell line (A549) Human TASP1 1:3~1:4 Negative Online Inquiry

Background

TASP1 Gene Knockout Cell Lines are innovative and specialized cellular models engineered to specifically disrupt the TASP1 gene, which encodes a crucial enzyme involved in cellular processes such as protein synthesis, regulation of cell cycle, and apoptosis. By employing advanced gene-editing technologies, these cell lines allow researchers to study the absence of TASP1 function, facilitating deeper insights into its role in various biological pathways and disease mechanisms.

The primary function of TASP1 is associated with the cleavage of target proteins, influencing their stability and localization. The gene knockout mechanism effectively silences the expression of TASP1, allowing for the observation of phenotypic changes and interactions at the molecular level. Researchers utilize these models to dissect the gene’s contribution to pathological conditions, such as cancers and neurodegenerative diseases, thereby setting the stage for novel therapeutic strategies.

The scientific importance of TASP1 Gene Knockout Cell Lines is underscored by their applicability in translational research and drug development. These cell lines serve as vital tools for screening potential drug candidates and understanding the implications of TASP1 dysregulation in disease processes. Their use extends beyond basic research, aiding in the identification of biomarkers and therapeutic targets relevant to clinical interventions.

One of the specific advantages these cell lines offer over alternative models is their precision in gene editing, ensuring reliable and reproducible results. Furthermore, the availability of validated phenotypic characterization strengthens their credibility, making them an invaluable asset in both academic and industrial laboratories.

Researchers and clinicians benefit greatly from the availability of TASP1 Gene Knockout Cell Lines, as they provide a powerful and sophisticated means to explore complex biochemical interactions and validate hypotheses about gene function. Their utility in generating reliable data supports innovations in healthcare, enhancing our understanding of cellular dynamics and therapeutic responses.

Our company specializes in the development of high-quality biological tools and cell lines, ensuring that researchers have access to cutting-edge resources that drive research outcomes and clinical advancements. We are committed to excellence and innovation, providing products that meet the highest scientific standards.

Please note that all services are for research use only. Not intended for any clinical use.

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