Gene: Scaf1
Official Full Name: SR-related CTD-associated factor 1provided by RGD
Gene Summary: Enables protein domain specific binding activity. Involved in mRNA processing and transcription by RNA polymerase II. Predicted to be located in nucleus. Biomarker of end stage renal disease. Orthologous to human SCAF1 (SR-related CTD associated factor 1). [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
GP00556 | Scaf1 gRNA1-gRNA2 KO plasmid | Scaf1 | $850 | |||
KO01295 | Scaf1 Knockout cell line (H9c2(2-1)) | Rat | Scaf1 | 1:3~1:4 | Negative | Online Inquiry |
Scaf1 Gene Knockout Cell Lines are genetically modified cell lines designed to selectively disrupt the Scaf1 gene, an important component in cellular signaling and structural integrity. By utilizing targeted gene editing technologies such as CRISPR/Cas9, these cell lines enable researchers to study the specific functions of the Scaf1 gene by observing how its absence affects cellular behavior, signaling pathways, proliferation, and differentiation.
The primary function of Scaf1 involves its role as a scaffold in cellular communication, facilitating interactions among various signaling molecules. When the Scaf1 gene is knocked out, researchers can investigate the downstream effects—unraveling the complex networks that govern cellular processes like apoptosis, stress responses, and metabolic pathways. This mechanism opens pathways to explore potential therapeutic targets for diseases linked to dysfunctional cellular signaling, such as cancer.
The scientific importance of Scaf1 Gene Knockout Cell Lines cannot be overstated; they serve as invaluable tools in both basic and applied research. In clinical settings, an understanding of the Scaf1 gene's role may pave the way for novel approaches in treating disorders where cellular signaling is compromised. These cell lines can be employed in drug discovery efforts and toxicology studies, thereby assisting researchers in the development of more effective therapeutic strategies.
What sets our Scaf1 Gene Knockout Cell Lines apart from existing alternatives is the rigor of our gene editing process, ensuring a high specificity of knockout while minimizing off-target effects. Additionally, our cell lines are readily adaptable to a variety of experimental conditions and compatible with high-throughput screening, enhancing their utility in diverse research contexts.
Researchers and clinicians should consider the Scaf1 Gene Knockout Cell Lines as essential for advancing their studies into gene function and cellular dynamics. By offering these cutting-edge tools, we invite scientists to push the boundaries of understanding in cellular biology. Our company specializes in providing high-quality biological products and is committed to supporting scientific innovations that transform healthcare and research.
Please note that all services are for research use only. Not intended for any clinical use.
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