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SNTB2 Knockout Cell Lines

Gene: SNTB2

Official Full Name: syntrophin beta 2provided by HGNC

Gene Summary: Dystrophin is a large, rod-like cytoskeletal protein found at the inner surface of muscle fibers. Dystrophin is missing in Duchenne Muscular Dystrophy patients and is present in reduced amounts in Becker Muscular Dystrophy patients. The protein encoded by this gene is a peripheral membrane protein found associated with dystrophin and dystrophin-related proteins. This gene is a member of the syntrophin gene family, which contains at least two other structurally-related genes. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO35313 SNTB2 Knockout cell line (HeLa) Human SNTB2 1:3~1:6 Negative Online Inquiry
KO35314 SNTB2 Knockout cell line (HCT 116) Human SNTB2 1:2~1:4 Negative Online Inquiry
KO35315 SNTB2 Knockout cell line (HEK293) Human SNTB2 1:3~1:6 Negative Online Inquiry
KO35316 SNTB2 Knockout cell line (A549) Human SNTB2 1:3~1:4 Negative Online Inquiry

Background

SNTB2 Gene Knockout Cell Lines are engineered cellular models designed to facilitate the study of the SNTB2 (syntrophin beta 2) gene, known for its role in signaling pathways and muscle function. By utilizing CRISPR/Cas9 gene-editing technology, these cell lines have been specifically modified to disrupt the expression of the SNTB2 gene, allowing researchers to investigate its physiological roles and contributions to various pathologies, particularly those related to neuromuscular function, signaling dysregulation, and cellular homeostasis.

The key function of SNTB2 Gene Knockout Cell Lines lies in their ability to mimic genetic deficiencies in controlled environments. Researchers can use these models to explore the repercussions of SNTB2 knockout on cellular processes, such as cytoskeletal organization, muscle contraction dynamics, and signal transduction pathways. This functionality makes them invaluable in elucidating the molecular mechanisms underlying diseases associated with this gene, including muscular dystrophies and other neuromuscular disorders.

The scientific importance of SNTB2 Gene Knockout Cell Lines extends to both basic research and clinical applications. They serve as critical tools for drug discovery, allowing scientists to assess therapeutic interventions that could potentially restore normal function in cells deficient in SNTB2. Additionally, these models play a vital role in genetic studies, contributing to our understanding of gene-environment interactions and the development of personalized medicine approaches.

Compared to alternative models, SNTB2 Gene Knockout Cell Lines offer precise genetic modification with minimal off-target effects, ensuring the validity of experimental results. Their reproducibility and ease of use further enhance their appeal, making them suitable for high-throughput screening applications.

For researchers and clinicians focused on muscle disorders or signal transduction research, SNTB2 Gene Knockout Cell Lines represent an indispensable resource for advancing knowledge and developing innovative therapies. Our company leverages extensive expertise in genetic engineering and cell culture technologies, providing high-quality products that meet the rigorous demands of scientific research. We are committed to supporting the scientific community by delivering tools that empower discovery and innovation.

Please note that all services are for research use only. Not intended for any clinical use.

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