Gene: SLC66A2
Official Full Name: solute carrier family 66 member 2provided by HGNC
Gene Summary: Predicted to be involved in phospholipid translocation and retrograde transport, endosome to Golgi. Predicted to be located in cytosol and membrane. Predicted to be active in endosome and trans-Golgi network. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO26207 | SLC66A2 Knockout cell line (HeLa) | Human | SLC66A2 | 1:3~1:6 | Negative | Online Inquiry |
KO26208 | SLC66A2 Knockout cell line (HCT 116) | Human | SLC66A2 | 1:2~1:4 | Negative | Online Inquiry |
KO26209 | SLC66A2 Knockout cell line (HEK293) | Human | SLC66A2 | 1:3~1:6 | Negative | Online Inquiry |
KO26210 | SLC66A2 Knockout cell line (A549) | Human | SLC66A2 | 1:3~1:4 | Negative | Online Inquiry |
SLC66A2 gene knockout cell lines are genetically modified cell lines in which the SLC66A2 gene has been specifically disrupted to study its role in human physiology and pathophysiology. The SLC66A2 gene encodes a sodium-dependent transport protein involved in the uptake of key metabolites and neurotransmitters, playing a crucial role in maintaining cellular homeostasis. The knockout of this gene allows for the detailed examination of its function and contributions to disease states, particularly in areas such as mental health disorders, metabolic syndromes, and neurodegenerative diseases.
These cell lines function by lacking the SLC66A2 protein, thereby creating a model to investigate the downstream effects of its absence. This facilitates research into the mechanisms of sodium-dependent transport processes and how alterations can lead to pathologies, as well as the potential development of therapeutics that target the SLC66A2-related pathways. The mechanistic insights garnered from using SLC66A2 knockout cell lines can lead to the identification of novel biomarkers or therapeutic targets.
Scientifically, the relevance of SLC66A2 gene knockout cell lines lies in their capacity to advance our understanding of complex physiological processes and their perturbations in diseases. They are invaluable in both basic research and preclinical studies that aim to elucidate the biological roles of this transporter and its potential as a drug target.
Compared to traditional wild-type cell lines, SLC66A2 knockout cell lines offer unique advantages, including the ability to isolate and study the specific impacts of the SLC66A2 gene loss on cellular function. This specificity can enhance the accuracy and reliability of experimental results, ultimately streamlining the research process.
Researchers and clinicians will find significant value in SLC66A2 knockout cell lines, as they provide an innovative platform for the exploration of therapeutic strategies and the evaluation of cellular responses in a controlled environment. By understanding the complexities of sodium-dependent transport mechanisms, scientists can contribute to the development of more targeted, effective treatments for a wide range of health issues.
Our company has extensive expertise in genetic modification technologies and is committed to providing high-quality biological research tools, such as the SLC66A2 gene knockout cell lines, to empower researchers in their quest to discover transformative insights in biomedical science.
Please note that all services are for research use only. Not intended for any clinical use.
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