Gene: SLC3A2
Official Full Name: solute carrier family 3 member 2provided by HGNC
Gene Summary: This gene is a member of the solute carrier family and encodes a cell surface, transmembrane protein. The protein exists as the heavy chain of a heterodimer, covalently bound through di-sulfide bonds to one of several possible light chains. The encoded transporter plays a role in regulation of intracellular calcium levels and transports L-type amino acids. Alternatively spliced transcript variants, encoding different isoforms, have been characterized. [provided by RefSeq, Nov 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO00140 | SLC3A2 Knockout cell line (HeLa) | Human | SLC3A2 | 1:3~1:6 | Negative | Online Inquiry |
KO09932 | SLC3A2 Knockout cell line (HCT 116) | Human | SLC3A2 | 1:2~1:4 | Negative | Online Inquiry |
KO09933 | SLC3A2 Knockout cell line (HEK293) | Human | SLC3A2 | 1:3~1:6 | Negative | Online Inquiry |
KO09934 | SLC3A2 Knockout cell line (A549) | Human | SLC3A2 | 1:3~1:4 | Negative | Online Inquiry |
SLC3A2 Gene Knockout Cell Lines are specialized cell lines in which the SLC3A2 gene has been precisely disrupted to study its functions and implications in various biological processes. SLC3A2, also known as solute carrier family 3 member 2, encodes a protein that is an essential component of amino acid transport systems in cells. By creating knockout models of SLC3A2, researchers can eliminate its influence, thereby allowing a more profound investigation into the physiological and pathological roles of amino acid transporters in cellular metabolism, drug resistance, and tumor progression.
The primary utility of SLC3A2 knockout cell lines lies in their ability to dissect the signaling pathways and metabolic adaptations that involve SLC3A2-mediated transport processes. Utilizing tools such as CRISPR-Cas9 gene editing technology, these models provide a robust platform for understanding how the absence of SLC3A2 affects cellular homeostasis, influences nutrient uptake, and alters response to therapeutic agents. This can be particularly significant in cancer research, where amino acid metabolism often shifts to support rapid cell growth.
Scientifically, SLC3A2 knockout cell lines represent an innovative avenue for studying complex diseases and conditions, positioning them as vital tools for both basic research and clinical applications. Compared to traditional methods such as RNA interference, these knockout models provide a more stable and permanent solution for gene disruption, enhancing experimental accuracy and reproducibility.
For researchers and clinicians, the value of SLC3A2 Gene Knockout Cell Lines lies in their capacity to uncover new biological mechanisms and pave the way for novel therapeutic strategies. Their use can facilitate the development of drugs targeting metabolic pathways that are critical in cancer and other metabolic disorders.
Our company brings extensive expertise in the development and application of gene-edited cell lines, ensuring that our SLC3A2 Gene Knockout Cell Lines meet the highest standards of quality and reliability for your research needs. With our commitment to advancing biomedical research, we are dedicated to supporting scientists in their exploration of gene function and disease mechanisms.
Please note that all services are for research use only. Not intended for any clinical use.
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