Gene: SLC35F3
Official Full Name: solute carrier family 35 member F3provided by HGNC
Gene Summary: Involved in thiamine transport. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO06814 | SLC35F3 Knockout cell line (HeLa) | Human | SLC35F3 | 1:3~1:6 | Negative | Online Inquiry |
KO06815 | SLC35F3 Knockout cell line (HCT 116) | Human | SLC35F3 | 1:2~1:4 | Negative | Online Inquiry |
KO06816 | SLC35F3 Knockout cell line (A549) | Human | SLC35F3 | 1:3~1:4 | Negative | Online Inquiry |
SLC35F3 Gene Knockout Cell Lines are genetically engineered human cell lines, specifically designed to exhibit a complete knockout of the SLC35F3 gene. This gene encodes a protein that plays a pivotal role in nucleotide-sugar transport across cellular membranes, which is essential for various biological processes, including glycosylation and cellular signaling. By removing the function of this gene, researchers can effectively study its impact on cellular functions and metabolic pathways, enabling comprehensive investigations into diseases related to glycosylation abnormalities.
The key mechanism behind these cell lines lies in the precise editing of the SLC35F3 gene using advanced CRISPR-Cas9 technology. This allows for a targeted disruption of the gene, leading to specific phenotypic changes and providing insights into gene function and regulatory networks within cells. Researchers can use these knockout lines to explore the effects on cell proliferation, differentiation, and response to environmental stimuli, making them a valuable tool for both basic research and therapeutic development.
The scientific importance of SLC35F3 Gene Knockout Cell Lines cannot be overstated. They have significant applications in understanding glycosylation in health and disease, including cancer progression, immunological responses, and metabolic disorders. By utilizing these cell lines, researchers can better elucidate the role of SLC35F3 in pathologies and potentially identify novel therapeutic targets.
What sets SLC35F3 Gene Knockout Cell Lines apart from alternative models is their specificity and reliability. The precise gene editing ensures a complete knockout, minimizing off-target effects that might confound results, which is a common challenge with less refined techniques. Additionally, the availability of high-quality, validated lines guarantees reproducible results across various experiments.
For researchers and clinicians delving into the complexities of gene function and looking to advance their investigations, SLC35F3 Gene Knockout Cell Lines offer a unique opportunity to gain deeper insights into critical biological processes. Enhanced understanding of the SLC35F3 gene's role can lead to breakthroughs in therapeutic strategies in various fields, including oncology and regenerative medicine.
Our company, with years of expertise in genetic engineering and cell line development, is committed to providing high-quality biological research products. We stand out as a trusted provider, ensuring that researchers have access to the best tools available to facilitate their groundbreaking work.
Please note that all services are for research use only. Not intended for any clinical use.
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