Gene: SLC25A6
Official Full Name: solute carrier family 25 member 6provided by HGNC
Gene Summary: This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein is implicated in the function of the permability transition pore complex (PTPC), which regulates the release of mitochondrial products that induce apoptosis. The human genome contains several non-transcribed pseudogenes of this gene. [provided by RefSeq, Jun 2013]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO07994 | SLC25A6 Knockout cell line (HeLa) | Human | SLC25A6 | 1:3~1:6 | Negative | Online Inquiry |
KO07995 | SLC25A6 Knockout cell line (HCT 116) | Human | SLC25A6 | 1:2~1:4 | Negative | Online Inquiry |
KO07996 | SLC25A6 Knockout cell line (HEK293) | Human | SLC25A6 | 1:3~1:6 | Negative | Online Inquiry |
KO07997 | SLC25A6 Knockout cell line (A549) | Human | SLC25A6 | 1:3~1:4 | Negative | Online Inquiry |
SLC25A6 Gene Knockout Cell Lines are genetically modified cell lines designed to facilitate the study of the SLC25A6 gene, which encodes the mitochondrial aspartate/glutamate transporter. These cell lines have undergone targeted gene editing techniques, such as CRISPR-Cas9, resulting in a complete knockout of SLC25A6. This product enables researchers to delve into the functional roles and biological significance of SLC25A6 in various cellular processes, including energy metabolism, apoptosis, and amino acid transport.
The primary functionality of these knockout cell lines revolves around their ability to provide a clearer understanding of the physiological consequences of SLC25A6 deficiency. Researchers can assess alterations in mitochondrial function and its implications for cellular homeostasis. Additionally, these cell lines serve as crucial models for exploring the impact of SLC25A6 on metabolic disorders and neurological diseases, where its dysregulation plays a significant role.
Scientifically, SLC25A6 Gene Knockout Cell Lines hold substantial importance in both research and clinical settings. Their application can extend to drug development, enabling the identification of potential therapeutic targets related to energy dysregulation. Furthermore, they offer valuable insights into the biochemical pathways influenced by the SLC25A6 transporter, thereby enhancing our understanding of fundamental biological processes.
One of the unique advantages of using SLC25A6 Gene Knockout Cell Lines is their specificity and reliability in experimental settings, providing clarity that alternative models may lack. Moreover, these cell lines can streamline the research process, reduce time and resource expenditure on preliminary experiments, and produce reproducible results essential for advancing scientific literature.
For researchers and clinicians alike, these knockout cell lines represent an invaluable tool for elucidating complex cellular mechanisms and developing innovative therapies. With expertise in genetic editing and cell line development, our company is committed to providing high-quality biological products that support cutting-edge research and the advancement of healthcare solutions.
Please note that all services are for research use only. Not intended for any clinical use.
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