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SLC25A28 Knockout Cell Lines

Gene: SLC25A28

Official Full Name: solute carrier family 25 member 28provided by HGNC

Gene Summary: Predicted to enable ferrous iron transmembrane transporter activity. Predicted to be involved in iron import into the mitochondrion. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO03658 SLC25A28 Knockout cell line (HeLa) Human SLC25A28 1:3~1:6 Negative Online Inquiry
KO03659 SLC25A28 Knockout cell line (HCT 116) Human SLC25A28 1:2~1:4 Negative Online Inquiry
KO03660 SLC25A28 Knockout cell line (HEK293) Human SLC25A28 1:3~1:6 Negative Online Inquiry
KO03661 SLC25A28 Knockout cell line (A549) Human SLC25A28 1:3~1:4 Negative Online Inquiry

Background

SLC25A28 Gene Knockout Cell Lines are an innovative biological tool designed for the detailed study of mitochondrial transport processes and their implications in cellular metabolism and disease. These cell lines are genetically modified to disrupt the SLC25A28 gene, which encodes a mitochondrial carrier protein involved in the regulation of metabolite transport across the inner mitochondrial membrane. By effectively knocking out this gene, researchers can elucidate the functional roles of SLC25A28 in cellular bioenergetics, signaling, and homeostasis.

The primary function of SLC25A28 is to facilitate the transport of key metabolites, such as carnitine and various amino acids, which are crucial for optimal mitochondrial function. The knockout model allows for the examination of compensatory mechanisms and metabolic alterations that occur when SLC25A28 is rendered inactive. This research is vital, as disruptions in mitochondrial transport are implicated in various metabolic disorders and cancers, highlighting SLC25A28 as a potential therapeutic target.

In clinical and research settings, these knockout cell lines are invaluable for experimental models investigating mitochondrial dysfunction, drug efficacy, and metabolic disorders. The ability to study the precise effects of SLC25A28 deletion offers insights that traditional models cannot provide, making them a unique asset for advancing our understanding of complex biological pathways.

What sets our SLC25A28 Gene Knockout Cell Lines apart from alternatives is the rigorous validation of these models, ensuring high specificity and reproducibility in experimental results. Our established protocols for cell culture and gene editing optimize usage and reliability, thus facilitating swift integration into ongoing research.

Researchers, clinicians, and pharmaceutical companies will find these cell lines essential for developing new therapeutic approaches targeting mitochondrial dysfunction. As a leader in gene editing technology, our company is committed to providing high-quality biological materials that support cutting-edge research and innovative healthcare solutions. Our expertise in the field ensures that customers receive products that foster breakthrough discoveries and advance scientific understanding.

Please note that all services are for research use only. Not intended for any clinical use.

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