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SLC16A10 Knockout Cell Lines

Gene: SLC16A10

Official Full Name: solute carrier family 16 member 10provided by HGNC

Gene Summary: SLC16A10 is a member of a family of plasma membrane amino acid transporters that mediate the Na(+)-independent transport of aromatic amino acids across the plasma membrane.[supplied by OMIM, Apr 2004]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO30436 SLC16A10 Knockout cell line (HCT 116) Human SLC16A10 1:2~1:4 Negative Online Inquiry
KO30437 SLC16A10 Knockout cell line (HEK293) Human SLC16A10 1:3~1:6 Negative Online Inquiry
KO30438 SLC16A10 Knockout cell line (A549) Human SLC16A10 1:3~1:4 Negative Online Inquiry

Background

SLC16A10 Gene Knockout Cell Lines are specialized cellular models in which the SLC16A10 gene has been precisely inactivated or "knocked out," providing researchers with a powerful tool to study the gene's biological functions and its implications in various physiological and pathological contexts. SLC16A10, part of the solute carrier family, encodes a transporter protein implicated in the uptake of monocarboxylates, which are critical for cellular metabolism and energy homeostasis. The precise knockout of this gene allows for the investigation of its role in metabolic disorders, cancer biology, and the transport mechanisms that govern cellular function.

One of the primary functions of SLC16A10 is to regulate the transportation of lactate and other metabolites across the plasma membrane, influencing both anaerobic and aerobic metabolism. By utilizing these knockout cell lines, researchers can explore compensatory mechanisms and metabolic shifts that occur in the absence of this transporter, thus elucidating the pathways affected by its loss. This has profound significance in clinical research where understanding metabolic dysregulation can lead to novel therapeutic approaches in cancer and metabolic syndrome.

Compared to traditional cell lines, the SLC16A10 knockout models provide targeted insights into gene-specific functions and interactions without the confounding effects of gene expression variability. This precision fosters reproducibility and reliability in experimental outcomes. Researchers can significantly streamline their studies in drug development, validation, and biomarker discovery with these unique models, expediting the foundational science necessary for advancing therapeutic strategies.

Moreover, the adoption of these knockout cell lines reflects a commitment to advancing the frontiers of biological research. Our company specializes in high-quality genetic models and provides comprehensive support, ensuring that our customers gain maximum value from their research endeavors. Investing in SLC16A10 Gene Knockout Cell Lines not only enhances experimental rigor but also aligns with modern approaches to understanding complex biological systems, making them an indispensable asset for researchers and clinicians alike.

Please note that all services are for research use only. Not intended for any clinical use.

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