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SKIC3 Knockout Cell Lines

Gene: SKIC3

Official Full Name: SKI3 subunit of superkiller complexprovided by HGNC

Gene Summary: This gene encodes a protein with twenty tetratricopeptide (TPR) repeats. Tetratricopeptide repeat containing motifs are found in a variety of proteins and may mediate protein-protein interactions and chaperone activity. Mutations in this gene are associated with trichohepatoenteric syndrome. [provided by RefSeq, Jul 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO14120 SKIC3 Knockout cell line (HeLa) Human SKIC3 1:3~1:6 Negative Online Inquiry
KO14121 SKIC3 Knockout cell line (HCT 116) Human SKIC3 1:2~1:4 Negative Online Inquiry
KO14122 SKIC3 Knockout cell line (HEK293) Human SKIC3 1:3~1:6 Negative Online Inquiry
KO14123 SKIC3 Knockout cell line (A549) Human SKIC3 1:3~1:4 Negative Online Inquiry

Background

SKIC3 Gene Knockout Cell Lines are advanced biological tools designed for researchers investigating the role of the SKIC3 gene in various biological processes. These cell lines have been meticulously engineered to possess a complete knockout of the SKIC3 gene, which facilitates the study of gene function, signaling pathways, and disease mechanisms. By utilizing CRISPR/Cas9 technology, the SKIC3 Gene Knockout Cell Lines ensure precise and efficient gene ablation, providing researchers with a reliable model to elucidate the physiological and pathological implications of SKIC3 knockdown.

The key mechanism underlying these cell lines involves the targeted modification of the gene's DNA sequence, resulting in the disruption of the gene's normal function. This genetic alteration allows for the assessment of phenotypic changes, gene interaction, and compensatory mechanisms that may emerge in the absence of SKIC3. In the laboratory, these cell lines can be used in a variety of applications, including drug screening, functional genomics, and basic biological research, with implications for understanding cancer biology, metabolic disorders, and signal transduction pathways.

What differentiates SKIC3 Gene Knockout Cell Lines from conventional cell models is their specificity and reproducibility. Unlike standard cell lines that may present mixed results due to genetic variability, the knockout ensures that researchers are examining the direct effects of the absence of SKIC3. Additionally, these cell lines undergo rigorous quality control to confirm the complete knockout and maintain consistent growth characteristics, thus ensuring reliable experimental outcomes.

The proprietary SKIC3 Gene Knockout Cell Lines provide unparalleled value to researchers and clinicians seeking to explore the complex roles of genetic factors in disease development and progression. The availability of a dedicated model for SKIC3 opens avenues for innovative research and therapeutic strategies, aligning with contemporary scientific endeavors aimed at unraveling the molecular underpinnings of health and disease.

With a commitment to advancing genetic research, our company's expertise in cell line development ensures that our products meet the highest standards, providing researchers with the tools necessary to drive discoveries in biological science.

Please note that all services are for research use only. Not intended for any clinical use.

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