Gene: SH3BP5L
Official Full Name: SH3 binding domain protein 5 likeprovided by HGNC
Gene Summary: Enables guanyl-nucleotide exchange factor activity. Predicted to be involved in intracellular signal transduction. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO25863 | SH3BP5L Knockout cell line (HeLa) | Human | SH3BP5L | 1:3~1:6 | Negative | Online Inquiry |
KO25864 | SH3BP5L Knockout cell line (HCT 116) | Human | SH3BP5L | 1:2~1:4 | Negative | Online Inquiry |
KO25865 | SH3BP5L Knockout cell line (HEK293) | Human | SH3BP5L | 1:3~1:6 | Negative | Online Inquiry |
KO25866 | SH3BP5L Knockout cell line (A549) | Human | SH3BP5L | 1:3~1:4 | Negative | Online Inquiry |
SH3BP5L Gene Knockout Cell Lines represent a valuable tool in cellular and molecular biology, specifically designed to facilitate the study of the SH3BP5L gene, which is implicated in various cellular processes including cell signaling and cytoskeletal dynamics. These genetically engineered cell lines allow researchers to explore the functional consequences of the absence of SH3BP5L, providing insights into its role in health and disease.
The primary mechanism of action for these knockout cell lines involves the targeted disruption of the SH3BP5L gene through CRISPR-Cas9 technology or other gene-editing methodologies, leading to a loss of function of the SH3BP5L protein. Researchers can utilize these cell lines to investigate downstream signaling pathways, assess alterations in cell behavior, and understand the molecular interplay in conditions such as cancer, neurodegenerative disorders, and autoimmunity.
The scientific importance of SH3BP5L Gene Knockout Cell Lines extends to their application in both basic research and translational studies. For instance, they are employed in drug discovery programs to identify potential therapeutic compounds that can modulate the pathways affected by SH3BP5L. Furthermore, by offering a model to study the gene's interaction with oncogenes or tumor suppressor genes, these cell lines play a crucial role in elucidating tumorigenesis mechanisms.
When compared to other knockout models, our SH3BP5L Gene Knockout Cell Lines are generated with high specificity and efficiency, minimizing off-target effects. This enhances the reliability of experimental results. Additionally, they are validated for consistent performance in various assays, offering researchers peace of mind regarding their experimental frameworks.
For researchers and clinicians aiming to deepen their understanding of cellular signaling or develop targeted therapies, the SH3BP5L Gene Knockout Cell Lines provide an efficient, robust, and scientifically relevant platform. Empowered by a commitment to quality and precision, our company specializes in delivering cutting-edge biological products and solutions that meet the needs of the scientific community.
Please note that all services are for research use only. Not intended for any clinical use.
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