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SH2D3A Knockout Cell Lines

Gene: SH2D3A

Official Full Name: SH2 domain containing 3Aprovided by HGNC

Gene Summary: Predicted to enable guanyl-nucleotide exchange factor activity and phosphotyrosine residue binding activity. Predicted to be involved in JNK cascade. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO02454 SH2D3A Knockout cell line (HeLa) Human SH2D3A 1:3~1:6 Negative Online Inquiry
KO02455 SH2D3A Knockout cell line (HCT 116) Human SH2D3A 1:2~1:4 Negative Online Inquiry
KO02456 SH2D3A Knockout cell line (HEK293) Human SH2D3A 1:3~1:6 Negative Online Inquiry
KO02457 SH2D3A Knockout cell line (A549) Human SH2D3A 1:3~1:4 Negative Online Inquiry

Background

SH2D3A Gene Knockout Cell Lines are specialized cellular models engineered to lack the SH2D3A gene (SH2 domain-containing protein 3A), which plays a crucial role in various signal transduction pathways. The targeted knockout of this gene allows researchers to delve into the functional consequences of its absence, providing unique insights into cellular processes such as immune response, signal transduction, and oncogenic pathways. By employing CRISPR-Cas9 technology for the precise deletion of SH2D3A, these cell lines facilitate robust studies on gene function, protein interactions, and cellular behavior, thereby establishing a versatile platform for experimental research.

The SH2D3A gene is implicated in processes that involve T-cell signaling and immune cell activation, making these knockout cell lines particularly advantageous for investigating the immune system's intricacies. In clinical research, understanding the implications of SH2D3A disruption may provide breakthroughs in targeting immune-related diseases, cancer therapies, and understanding autoimmune conditions. Researchers can utilize these cell lines to assess the influence of SH2D3A on cellular proliferation, differentiation, and response to stimuli, thereby underscoring the relevance of this product in translational research.

Compared to traditional wild-type cell lines, SH2D3A Gene Knockout Cell Lines offer researchers the unparalleled advantage of studying the phenotypic effects of SH2D3A absence without confounding variables, allowing for highly controlled experiments. Furthermore, these knockout models contribute to reproducibility and consistency in experimental outcomes, enhancing the credibility of research findings.

Investing in SH2D3A Gene Knockout Cell Lines empowers researchers and clinicians alike, providing them with the necessary tools to uncover novel therapeutic targets and advance the understanding of complex biological systems. At [Your Company Name], we pride ourselves on our commitment to providing high-quality, innovative biological products that facilitate groundbreaking research in genomics and cell biology. With our expertise and customer-centric approach, we strive to be your trusted partner in scientific discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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