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SGF29 Knockout Cell Lines

Gene: SGF29

Official Full Name: SAGA complex associated factor 29provided by HGNC

Gene Summary: CCDC101 is a subunit of 2 histone acetyltransferase complexes: the ADA2A (TADA2A; MIM 602276)-containing (ATAC) complex and the SPT3 (SUPT3H; MIM 602947)-TAF9 (MIM 600822)-GCN5 (KAT2A; MIM 602301)/PCAF (KAT2B; MIM 602303) acetylase (STAGA) complex. Both of these complexes contain either GCN5 or PCAF, which are paralogous acetyltransferases (Wang et al., 2008 [PubMed 18838386]).[supplied by OMIM, Apr 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO30895 SGF29 Knockout cell line (HeLa) Human SGF29 1:3~1:6 Negative Online Inquiry
KO30896 SGF29 Knockout cell line (HCT 116) Human SGF29 1:2~1:4 Negative Online Inquiry
KO30897 SGF29 Knockout cell line (HEK293) Human SGF29 1:3~1:6 Negative Online Inquiry
KO30898 SGF29 Knockout cell line (A549) Human SGF29 1:3~1:4 Negative Online Inquiry

Background

SGF29 Gene Knockout Cell Lines are engineered cellular models specifically designed to investigate the functional roles of the SGF29 gene in both normal physiology and various disease states. These knockout models serve as powerful tools for elucidating gene function by providing researchers with a system where SGF29 expression is completely ablated, allowing for the study of pathways and interactions that are otherwise masked by the gene's activity.

The key mechanism behind these cell lines involves CRISPR-Cas9 gene-editing technology, which precisely targets and excises the SGF29 gene from the host genome, resulting in the production of cell lines with stable mutations. This enables scientists to explore the consequences of SGF29 loss of function on cellular processes such as transcriptional regulation, chromatin remodeling, and cellular differentiation. Consequently, these models facilitate a deeper understanding of the biological mechanisms underlying diseases, particularly those where SGF29 is implicated, such as certain cancers and metabolic disorders.

The scientific importance of SGF29 Gene Knockout Cell Lines extends across various research and clinical applications, making them indispensable for therapeutic development and biomarker discovery. Their unique ability to replicate human disease conditions in vitro provides a reliable platform for drug screening, target validation, and pathway analysis.

What sets SGF29 knockout lines apart from alternative models is their high degree of specificity and reliability, coupled with the robustness of CRISPR technology. Unlike other forms of genetic manipulation, our knockout lines minimize off-target effects and provide consistent, reproducible results, essential for high-quality research outputs.

For researchers and clinicians seeking to advance their understanding of gene function and its implications for human health, SGF29 Gene Knockout Cell Lines represent a valuable, scientifically rigorous option. They not only promise to accelerate discovery but also position users at the forefront of genetic research.

Our company's commitment to excellence in genetic engineering ensures that we deliver top-tier biological products that meet stringent quality standards, empowering researchers to drive innovation in their fields.

Please note that all services are for research use only. Not intended for any clinical use.

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