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SERTAD4 Knockout Cell Lines

Gene: SERTAD4

Official Full Name: SERTA domain containing 4provided by HGNC

Gene Summary: Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO14198 SERTAD4 Knockout cell line (HeLa) Human SERTAD4 1:3~1:6 Negative Online Inquiry
KO14199 SERTAD4 Knockout cell line (HEK293) Human SERTAD4 1:3~1:6 Negative Online Inquiry
KO14200 SERTAD4 Knockout cell line (A549) Human SERTAD4 1:3~1:4 Negative Online Inquiry

Background

SERTAD4 Gene Knockout Cell Lines are specialized cellular models engineered to lack the expression of the SERTAD4 (SERTA domain-containing protein 4) gene. These cell lines are invaluable tools for studying the role of SERTAD4 in various biological processes, particularly those linked to signal transduction and transcriptional regulation in cellular contexts. The knockout mechanism is typically achieved through CRISPR-Cas9 gene-editing technology, which allows for precise alteration of specific genomic sequences, thus enabling researchers to observe the resulting phenotypic changes and alterations in cellular behaviors.

The primary function of these knockout cell lines is to elucidate the physiological and pathological roles of the SERTAD4 protein, which has been implicated in cancer progression and developmental processes. By integrating in vitro studies with these cell lines, researchers can investigate the downstream effects of SERTAD4 absence on cellular pathways, gene expression profiles, and response to pharmacological agents.

The scientific importance of SERTAD4 Gene Knockout Cell Lines extends into both basic research and clinical applications. In a research setting, these lines facilitate the exploration of gene function and regulatory networks, offering insights that could translate into therapeutic targets for diseases where SERTAD4 plays a role, such as certain cancers. Clinically, they can contribute to drug development by enabling the screening of compounds that may specifically target pathways influenced by SERTAD4.

Compared to traditional cell models, such as wild-type or overexpressing cell lines, the SERTAD4 Gene Knockout Cell Lines offer unique advantages, including the ability to study loss-of-function phenotypes directly in a controlled environment. This specificity allows for more accurate conclusions regarding the gene’s role and its potential interactions within complex networks.

For researchers and clinicians alike, these established knockout cell lines significantly streamline experimental workflows while enhancing the reliability of results in genetic and pharmacological studies. This product represents a crucial advancement in the toolkit available for molecular biology research.

Our company is dedicated to advancing the field of life sciences through innovative genetic models and tools, ensuring researchers have access to high-quality products that empower groundbreaking discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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