Gene: SDF2
Official Full Name: stromal cell derived factor 2provided by HGNC
Gene Summary: The protein encoded by this gene is believed to be a secretory protein. It has regions of similarity to hydrophilic segments of yeast mannosyltransferases. Its expression is ubiquitous and the gene appears to be relatively conserved among mammals. Alternate splicing results in both coding and non-coding variants. A pseudogene of this gene is located on chromosome 15. [provided by RefSeq, Dec 2011]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO35484 | SDF2 Knockout cell line (HeLa) | Human | SDF2 | 1:3~1:6 | Negative | Online Inquiry |
KO35485 | SDF2 Knockout cell line (HCT 116) | Human | SDF2 | 1:2~1:4 | Negative | Online Inquiry |
KO35486 | SDF2 Knockout cell line (HEK293) | Human | SDF2 | 1:3~1:6 | Negative | Online Inquiry |
KO35487 | SDF2 Knockout cell line (A549) | Human | SDF2 | 1:3~1:4 | Negative | Online Inquiry |
SDF2 gene knockout cell lines are a revolutionary tool in molecular biology that allow researchers to study the functional role of the SDF2 gene through the deletion of its coding sequence. These cell lines are meticulously engineered to lack SDF2 expression, facilitating the exploration of its biological pathways, regulatory mechanisms, and contributions to various physiological processes. The precise engineering of these knockout models is often achieved using CRISPR/Cas9 technology, ensuring reliable and reproducible results for downstream applications.
The primary function of the SDF2 gene has been associated with critical cellular processes, including cell signaling, apoptosis, and response to stress. By using these knockout cell lines, researchers can delineate the specific roles SDF2 plays in cellular behavior, elucidating how its absence alters vital signaling cascades and impacts cellular homeostasis. This makes SDF2 knockout models invaluable for a wide array of research applications, such as cancer biology, immunology, and regenerative medicine, where SDF2 may play pivotal roles in tumor progression or immune response dynamics.
Compared to conventional gene targeting approaches, utilizing SDF2 gene knockout cell lines offers distinct advantages. They provide a stable genetic background that simplifies experimental setup and data interpretation, enabling reproducibility across studies. Furthermore, these cell lines can be utilized in high-throughput screening formats, significantly accelerating the drug discovery process or therapeutic interventions targeting the SDF2 pathway.
For researchers and clinicians focused on gaining deeper insights into gene function and the underlying pathology of diseases, SDF2 gene knockout cell lines present an essential resource. They empower scientific inquiry with a level of precision that enhances understanding and drives innovation, ultimately aiming to translate findings into clinical applications that improve patient outcomes.
As a leader in the development of advanced cellular models, our company is committed to providing high-quality biological products that support rigorous scientific research. Our expertise in cell line engineering ensures that researchers can depend on our SDF2 knockout cell lines for accuracy and performance in their studies.
Please note that all services are for research use only. Not intended for any clinical use.
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