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SCAMP1 Knockout Cell Lines

Gene: SCAMP1

Official Full Name: secretory carrier membrane protein 1provided by HGNC

Gene Summary: This gene product belongs to the SCAMP family of proteins, which are secretory carrier membrane proteins. They function as carriers to the cell surface in post-golgi recycling pathways. Different family members are highly related products of distinct genes, and are usually expressed together. These findings suggest that these protein family members may function at the same site during vesicular transport rather than in separate pathways. A pseudogene of this gene has been defined on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO02049 SCAMP1 Knockout cell line (HeLa) Human SCAMP1 1:3~1:6 Negative Online Inquiry
KO02050 SCAMP1 Knockout cell line (HCT 116) Human SCAMP1 1:2~1:4 Negative Online Inquiry
KO02051 SCAMP1 Knockout cell line (HEK293) Human SCAMP1 1:3~1:6 Negative Online Inquiry
KO02052 SCAMP1 Knockout cell line (A549) Human SCAMP1 1:3~1:4 Negative Online Inquiry

Background

SCAMP1 Gene Knockout Cell Lines are specialized cellular models engineered to lack the SCAMP1 (Secretory Cluster-Associated Membrane Protein 1) gene, which plays a crucial role in various cellular processes, including exocytosis and membrane trafficking. By utilizing CRISPR/Cas9 technology, these knockout cell lines provide researchers with a precise tool to investigate the functional implications of SCAMP1 depletion, offering insights into its role in cellular dynamics and signaling pathways.

The primary function of SCAMP1 is to facilitate the trafficking of vesicles and the vesicle fusion process, thus influencing the secretion of numerous biologically active molecules. Upon knockout, alterations to these processes can be rigorously studied in a controlled environment, enabling researchers to observe changes in vesicular transport, secretion dynamics, and their potential downstream effects on cell physiology. This mechanistic understanding is critical for elucidating the pathophysiological roles of SCAMP1 in various diseases, including neurodegenerative disorders and cancer.

The scientific importance of SCAMP1 Gene Knockout Cell Lines extends to both basic research and clinical applications. They serve as essential tools for investigating the biochemical pathways associated with membrane dynamics and for developing novel therapeutic strategies aimed at modulating these pathways. By offering a defined genetic background, these cell lines enhance reproducibility in experimental results, making them invaluable for a wide range of studies in cell biology, pharmacology, and disease modeling.

Compared to alternative models, our SCAMP1 Gene Knockout Cell Lines offer unmatched quality and robustness, backed by extensive validation and characterization. This ensures consistency in your experiments and more reliable interpretative data. Additionally, they come with comprehensive technical support and documentation, providing peace of mind for researchers embarking on complex studies.

In conclusion, SCAMP1 Gene Knockout Cell Lines are not just another tool but a pivotal resource for discerning the intricate roles of membrane proteins in health and disease. Our company is committed to providing cutting-edge biological products, emphasizing the importance of rigorous scientific inquiry, innovation, and customer satisfaction. Invest in SCAMP1 Gene Knockout Cell Lines to enhance your research and cultivate groundbreaking discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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