Gene: SCAI
Official Full Name: suppressor of cancer cell invasionprovided by HGNC
Gene Summary: This gene encodes a regulator of cell migration. The encoded protein appears to function in the RhoA (ras homolog gene family, member A)-Dia1 (diaphanous homolog 1) signal transduction pathway. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO14331 | SCAI Knockout cell line (HeLa) | Human | SCAI | 1:3~1:6 | Negative | Online Inquiry |
KO14332 | SCAI Knockout cell line (HCT 116) | Human | SCAI | 1:2~1:4 | Negative | Online Inquiry |
KO14333 | SCAI Knockout cell line (HEK293) | Human | SCAI | 1:3~1:6 | Negative | Online Inquiry |
KO14334 | SCAI Knockout cell line (A549) | Human | SCAI | 1:3~1:4 | Negative | Online Inquiry |
SCAI Gene Knockout Cell Lines are genetically modified cell models that enable researchers to study the specific roles of the SCAI (suppressor of cancer cell invasion) gene in cellular processes relevant to cancer biology, development, and disease. By using CRISPR/Cas9 technology, these cell lines have been engineered to disrupt the expression of the SCAI gene, providing a powerful tool for examining the resulting phenotypic changes associated with SCAI deficiency.
The key function of SCAI Gene Knockout Cell Lines lies in their ability to facilitate controlled investigation of pathways and mechanisms influenced by the SCAI gene. Researchers can explore SCAI's role in regulation of epithelial-mesenchymal transition (EMT), its impact on invasiveness and metastatic potential in cancer cells, or its involvement in other signaling pathways. The targeted knockout allows for precise functional assays, enabling scientists to delineate the gene's involvement in crucial cellular activities such as migration, growth, and apoptosis.
The scientific importance of SCAI Gene Knockout Cell Lines extends to various applications in both research and clinical settings. They serve as invaluable models for drug discovery and screening, particularly in identifying potential therapeutic interventions for metastatic cancers. Additionally, these cell lines aid in elucidating the molecular mechanisms underlying malignancy, providing foundational knowledge that can inform clinical strategies.
Compared to generic cell lines, SCAI Gene Knockout Cell Lines boast several unique advantages, including their specificity in targeting a particular gene and the ability to generate reproducible data that directly reflects the impact of gene knockout on cellular behavior. This specificity reduces background noise in experiments, thus enhancing the reliability of results.
For researchers and clinicians focused on cancer biology and therapeutic development, SCAI Gene Knockout Cell Lines offer a distinct combination of reliability, precision, and functional insight, making them a critical asset in advancing our understanding of cancer mechanisms and treatment strategies. Our company prides itself on providing high-quality genetic models developed through rigorous protocols, ensuring robust performance and reproducibility for all scientific inquiries.
Please note that all services are for research use only. Not intended for any clinical use.
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