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SAMD5 Knockout Cell Lines

Gene: SAMD5

Official Full Name: sterile alpha motif domain containing 5provided by HGNC

Gene Summary: Predicted to be involved in regulation of intracellular signal transduction. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO14369 SAMD5 Knockout cell line (HCT 116) Human SAMD5 1:2~1:4 Negative Online Inquiry
KO14370 SAMD5 Knockout cell line (HEK293) Human SAMD5 1:3~1:6 Negative Online Inquiry
KO14371 SAMD5 Knockout cell line (A549) Human SAMD5 1:3~1:4 Negative Online Inquiry

Background

SAMD5 Gene Knockout Cell Lines are engineered cell lines in which the SAMD5 gene has been selectively disrupted using CRISPR-Cas9 technology, allowing for the study of gene function and its associated pathways in a controlled environment. These cell lines serve as a valuable experimental model for researchers investigating the role of SAMD5 in various biological processes, including cellular senescence, stress response, and cancer biology.

The key mechanism of action of SAMD5 gene knockout involves the elimination of a gene known to be involved in the regulation of RNA processing and genome stability. This alteration enables researchers to observe phenotypic changes and functional outcomes, thereby elucidating the cellular mechanisms impacted by the absence of SAMD5. As a result, these knockout cell lines provide a robust platform for understanding the contributions of this gene to cellular behavior and disease mechanisms.

The scientific significance of SAMD5 gene knockout cell lines lies in their potential applications across a variety of research fields. They can be pivotal in cancer research, where understanding the role of tumor suppressor genes provides insights into tumor development and progression. Furthermore, these cell lines can facilitate drug development processes, helping to identify novel therapeutic targets or assess the efficacy of existing treatments.

When compared to alternative methods, such as traditional RNA interference or unmodified cell lines, SAMD5 gene knockout cell lines offer higher specificity, stability, and reproducibility of results. This specificity minimizes off-target effects, allowing researchers to draw more accurate conclusions regarding gene function and its implications in disease.

For researchers and clinicians, the ability to work with a precisely edited cell line that mimics relevant biological conditions enhances their experimental designs and outcomes. SAMD5 Gene Knockout Cell Lines are not just tools; they are essential allies in groundbreaking research that seeks to unravel the complexities of gene function in health and disease.

Our company, equipped with a strong foundation in gene editing technologies, specializes in providing high-quality biological products that empower scientific discovery and innovation. We take pride in our commitment to delivering precision-engineered models that meet the needs of the research community, fostering advancements across a broad spectrum of applications.

Please note that all services are for research use only. Not intended for any clinical use.

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