Home / RREB1 Knockout Cell Lines

RREB1 Knockout Cell Lines

Gene: RREB1

Official Full Name: ras responsive element binding protein 1provided by HGNC

Gene Summary: The protein encoded by this gene is a zinc finger transcription factor that binds to RAS-responsive elements (RREs) of gene promoters. It has been shown that the calcitonin gene promoter contains an RRE and that the encoded protein binds there and increases expression of calcitonin, which may be involved in Ras/Raf-mediated cell differentiation. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO35569 RREB1 Knockout cell line (HeLa) Human RREB1 1:3~1:6 Negative Online Inquiry
KO35570 RREB1 Knockout cell line (HCT 116) Human RREB1 1:2~1:4 Negative Online Inquiry
KO35571 RREB1 Knockout cell line (HEK293) Human RREB1 1:3~1:6 Negative Online Inquiry
KO35572 RREB1 Knockout cell line (A549) Human RREB1 1:3~1:4 Negative Online Inquiry

Background

RREB1 Gene Knockout Cell Lines are engineered biological tools designed to study the functional role of the RREB1 gene in cellular processes and disease mechanisms. RREB1, or Ras Responsive Element Binding Protein 1, is a transcription factor implicated in various biological functions, including cell proliferation, differentiation, and migration. By employing CRISPR/Cas9 technology, these knockout cell lines facilitate the precise deletion of the RREB1 gene, enabling researchers to investigate the gene’s contribution to molecular pathways and its involvement in certain cancers and other pathological states.

The primary function of RREB1 Gene Knockout Cell Lines lies in their ability to elucidate the biological consequences of RREB1 absence. Upon gene knockout, researchers can observe alterations in signaling pathways, changes in gene expression profiles, and modifications in phenotypic characteristics, which are crucial for understanding the disease mechanisms associated with aberrant RREB1 activity. The versatility of these cell lines also allows for their application in drug discovery, where investigators can screen compounds for effects on cellular processes modulated by RREB1.

The scientific importance of RREB1 Gene Knockout Cell Lines extends into both research and clinical settings, providing valuable insights into cancer biology and other diseases linked to RREB1 dysfunction. Unlike traditional methods such as RNA interference, which provide only transient knockdown, the knockout nature of these cell lines allows for stable, long-term studies of gene function, making them particularly valuable for clarity in experimental outcomes.

Moreover, these knockout cell lines offer distinct advantages over alternatives, including enhanced specificity, the ability to generate more reproducible data, and suitability for a broader range of experimental applications, from basic research to therapeutic development. This reliability and precision make them essential tools for researchers looking to delve deeper into the genomics of RREB1 and its role in disease.

In conclusion, RREB1 Gene Knockout Cell Lines represent a powerful asset for scientists and clinicians who aim to enhance their understanding of gene function and its implications in health and disease. Our company, with its strong foundation in genetic engineering and commitment to advancing biological research, is dedicated to providing high-quality products that empower innovative scientific exploration.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.