Gene: RRAGC
Official Full Name: Ras related GTP binding Cprovided by HGNC
Gene Summary: This gene encodes a member of the GTR/RAG GTP-binding protein family. The encoded protein is a monomeric guanine nucleotide-binding protein which forms a heterodimer with RRAGA and RRAGB and is primarily localized to the cytoplasm. The encoded protein promotes intracellular localization of the mTOR complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO09209 | RRAGC Knockout cell line (HeLa) | Human | RRAGC | 1:3~1:6 | Negative | Online Inquiry |
KO09210 | RRAGC Knockout cell line (HCT 116) | Human | RRAGC | 1:2~1:4 | Negative | Online Inquiry |
KO09211 | RRAGC Knockout cell line (HEK293) | Human | RRAGC | 1:3~1:6 | Negative | Online Inquiry |
KO09212 | RRAGC Knockout cell line (A549) | Human | RRAGC | 1:3~1:4 | Negative | Online Inquiry |
RRAGC Gene Knockout Cell Lines are genetically engineered cell models designed to facilitate the study of the RRAGC gene and its influences on cellular processes, particularly those associated with mTOR signaling, metabolism, and cell growth. By utilizing CRISPR-Cas9 technology, these knockout cell lines effectively silence the gene, allowing for the investigation of its role in various biological pathways and disease mechanisms.
The key function of RRAGC Gene Knockout Cell Lines lies in their ability to mimic the effects of gene loss in a controlled environment, enabling researchers to examine alterations in cellular behavior and contribute to a more profound understanding of the regulatory networks that govern cellular growth and nutrient sensing. Through the suppression of RRAGC, which is known to play a critical role in integrating signals from amino acids to mTOR, these cell lines present an opportunity to explore therapeutic targets in cancer and metabolic disorders.
From a scientific perspective, these knockout cell lines are invaluable in both research and clinical applications. They provide a scalable platform for drug screening and can be pivotal in elucidating novel pathways that could be targeted for therapeutic interventions. Researchers can apply the insights gained from these models to develop more effective treatments for a range of diseases linked to aberrant mTOR signaling.
What sets RRAGC Gene Knockout Cell Lines apart from other genetic models is their high specificity and efficiency in gene editing, which reduces off-target effects and enhances experimental reliability. Moreover, considering the growing interest in personalized medicine, these cell lines allow for tailored investigations that can lead to advancements in targeted therapies.
For researchers and clinicians alike, the ability to use a directly relevant model that closely mirrors human physiology makes these cell lines a crucial asset for enhancing our understanding of various pathophysiological conditions. Our company specializes in providing high-quality genetic tools, ensuring that all products are rigorously validated for reproducibility and performance. Trust in our expertise to support your research endeavors and drive innovation in the biomedical field.
Please note that all services are for research use only. Not intended for any clinical use.
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