Gene: RPS6KA1
Official Full Name: ribosomal protein S6 kinase A1provided by HGNC
Gene Summary: This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO10502 | RPS6KA1 Knockout cell line (HeLa) | Human | RPS6KA1 | 1:3~1:6 | Negative | Online Inquiry |
KO10503 | RPS6KA1 Knockout cell line (HCT 116) | Human | RPS6KA1 | 1:2~1:4 | Negative | Online Inquiry |
KO10504 | RPS6KA1 Knockout cell line (HEK293) | Human | RPS6KA1 | 1:3~1:6 | Negative | Online Inquiry |
KO10505 | RPS6KA1 Knockout cell line (A549) | Human | RPS6KA1 | 1:3~1:4 | Negative | Online Inquiry |
RPS6KA1 Gene Knockout Cell Lines are genetically engineered cellular models where the RPS6KA1 gene has been specifically inactivated or "knocked out." This innovative tool allows researchers to study the biological functions and regulatory mechanisms of RPS6KA1, a gene encoding the ribosomal protein S6 kinase, which plays a crucial role in various cellular processes, including cell growth, proliferation, and survival. The knockout of this gene enables the examination of its contributions to pathways involved in tumorigenesis, neuronal signaling, and metabolic regulation.
These cell lines function by disrupting the normal expression of RPS6KA1, thereby allowing researchers to observe phenotypic changes resulting from its absence. By employing various assays, scientists can explore downstream effects on signaling pathways, gene expression alterations, and potential compensatory mechanisms that might arise. This makes RPS6KA1 Knockout Cell Lines essential for dissecting the gene’s roles in health and disease, particularly within cancer biology and neurodegenerative research.
The significance of RPS6KA1 knockout models extends to numerous research applications, such as drug discovery, functional genomics, and personalized medicine strategies. They provide invaluable insight into RPS6KA1-related pathways and proteins, offering a better understanding of their molecular interactions and potential as therapeutic targets.
What sets our RPS6KA1 Gene Knockout Cell Lines apart from alternatives is their precise gene targeting, consistent cell line stability, and the availability of comprehensive validation data, ensuring reliability in experimental designs. Furthermore, these models support high-throughput screening, making them adaptable for extensive research endeavors.
For researchers and clinicians, the ability to utilize RPS6KA1 knockout cell lines enhances the exploration of pathogenic mechanisms and the identification of novel drug targets, ultimately contributing to advancements in disease treatment and prevention. Our company specializes in high-quality biological products backed by rigorous scientific research, ensuring that you receive top-tier resources to propel your work forward.
Please note that all services are for research use only. Not intended for any clinical use.
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