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RP9 Knockout Cell Lines

Gene: RP9

Official Full Name: RP9 pre-mRNA splicing factorprovided by HGNC

Gene Summary: The protein encoded by this gene can be bound and phosphorylated by the protooncogene PIM1 product, a serine/threonine protein kinase . This protein localizes in nuclear speckles containing the splicing factors, and has a role in pre-mRNA splicing. CBF1-interacting protein (CIR), a corepressor of CBF1, can also bind to this protein and effects alternative splicing. Mutations in this gene result in autosomal dominant retinitis pigmentosa-9. This gene has a pseudogene (GeneID: 441212), which is located in tandem array approximately 166 kb distal to this gene. [provided by RefSeq, Sep 2009]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO35589 RP9 Knockout cell line (HeLa) Human RP9 1:3~1:6 Negative Online Inquiry
KO35590 RP9 Knockout cell line (HCT 116) Human RP9 1:2~1:4 Negative Online Inquiry
KO35591 RP9 Knockout cell line (HEK293) Human RP9 1:3~1:6 Negative Online Inquiry
KO35592 RP9 Knockout cell line (A549) Human RP9 1:3~1:4 Negative Online Inquiry

Background

RP9 Gene Knockout Cell Lines are engineered cellular models specifically designed for the study of gene function and disease mechanisms. These cell lines are created using advanced CRISPR-Cas9 gene editing technology to selectively knock out the RP9 gene, a candidate implicated in various cellular processes, including apoptosis and cellular signaling pathways. By deactivating the RP9 gene, researchers can analyze the effects on cellular behaviors, providing insights into the gene's role in health and disease.

The primary function of the RP9 Gene Knockout Cell Lines is to facilitate in-depth studies of gene expression, cellular responses, and potential therapeutic targets. Through the use of these knockout cell lines, scientists can investigate how the absence of the RP9 gene alters cellular dynamics, leading to a better understanding of its physiological relevance. This model is particularly valuable in research focused on oncology, neurology, and immunology, where gene regulation is crucial for disease development and progression.

In clinical and research settings, these cell lines serve as a powerful tool for drug discovery. They allow for high-throughput screening of compounds that can potentially restore or compensate for the lost function of the RP9 gene. In comparison to traditional methods such as siRNA knockdowns, RP9 Gene Knockout Cell Lines provide a more stable and permanent solution for studying gene function, which enhances the reliability of data obtained.

One of the most compelling advantages of using RP9 Gene Knockout Cell Lines is the specificity and robustness afforded by the CRISPR technology employed. The precision of Cas9-mediated gene editing reduces off-target effects and improves reproducibility, making experiments more efficient and yielding clearer results. Researchers are increasingly aware of the importance of reliable models, and our product meets this need with unparalleled accuracy.

For researchers and clinicians aiming to elucidate the complexities of gene function and advance therapeutic approaches, the RP9 Gene Knockout Cell Lines represent an invaluable resource. Our commitment to scientific advancement is reflected in the quality and rigor of our products, which are backed by a team of experts in molecular biology and genetics. Choosing our cell lines ensures that you are utilizing top-tier resources to elevate your research to the next level.

Please note that all services are for research use only. Not intended for any clinical use.

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