Gene: RNF31
Official Full Name: ring finger protein 31provided by HGNC
Gene Summary: The protein encoded by this gene contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-DNA and protein-protein interactions. The encoded protein is the E3 ubiquitin-protein ligase component of the linear ubiquitin chain assembly complex. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2015]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO05292 | RNF31 Knockout cell line (HeLa) | Human | RNF31 | 1:3~1:6 | Negative | Online Inquiry |
KO05293 | RNF31 Knockout cell line (HCT 116) | Human | RNF31 | 1:2~1:4 | Negative | Online Inquiry |
KO05294 | RNF31 Knockout cell line (HEK293) | Human | RNF31 | 1:3~1:6 | Negative | Online Inquiry |
KO05295 | RNF31 Knockout cell line (A549) | Human | RNF31 | 1:3~1:4 | Negative | Online Inquiry |
RNF31 Gene Knockout Cell Lines are specialized cell culture models that have been genetically engineered to silence the RNF31 gene, a critical player in cellular processes such as protein ubiquitination, cell cycle regulation, and apoptosis. By utilizing CRISPR/Cas9 technology, these knockout cell lines allow researchers to investigate the function of RNF31 with heightened precision. The mechanism behind their operation involves the targeted disruption of the RNF31 coding sequence, thus leading to the absence of the RNF31 protein and facilitating the observation of cellular responses under controlled experimental conditions.
The scientific importance of RNF31 Gene Knockout Cell Lines is profound, particularly in the context of cancer research, immunology, and neurobiology. These models provide invaluable insights into the pathophysiological roles of RNF31, which is implicated in various diseases, including cancer and autoimmune disorders. By studying these knockout lines, researchers can explore potential therapeutic targets and pathways influenced by RNF31, pushing the boundaries of molecular biology and pharmacology.
What sets RNF31 Gene Knockout Cell Lines apart from alternative genetic models is their validated knockout efficiencies, minimal off-target effects, and consistent reproducibility across experiments. Unlike traditional siRNA or shRNA approaches that may lead to partial gene silencing, these knockout lines offer a complete cessation of RNF31 expression, ensuring clear and interpretable results. Furthermore, these cell lines are compatible with a wide range of assays and experimental conditions, enhancing their applicability in various research fields.
For researchers and clinicians striving for innovation and rigorous experimental reliability, RNF31 Gene Knockout Cell Lines present an essential tool. Their value lies not only in elucidating complex biological mechanisms but also in laying the groundwork for novel therapeutic strategies. With extensive experience in the development of genetically modified cell lines, our company is committed to providing high-quality biological products that support the advancement of scientific discovery.
Please note that all services are for research use only. Not intended for any clinical use.
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