Gene: RNF126
Official Full Name: ring finger protein 126provided by HGNC
Gene Summary: The protein encoded by this gene contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO20177 | RNF126 Knockout cell line (HeLa) | Human | RNF126 | 1:3~1:6 | Negative | Online Inquiry |
KO20178 | RNF126 Knockout cell line (HCT 116) | Human | RNF126 | 1:2~1:4 | Negative | Online Inquiry |
KO20179 | RNF126 Knockout cell line (HEK293) | Human | RNF126 | 1:3~1:6 | Negative | Online Inquiry |
KO20180 | RNF126 Knockout cell line (A549) | Human | RNF126 | 1:3~1:4 | Negative | Online Inquiry |
RNF126 Gene Knockout Cell Lines represent a cutting-edge tool for investigating gene function through targeted gene disruption. Created using CRISPR-Cas9 technology, these cell lines possess precise mutations in the RNF126 gene, which encodes a protein implicated in various cellular processes, including protein ubiquitination and DNA damage response mechanisms. By harnessing the capabilities of these knockout models, researchers can explore the downstream effects of RNF126 deficiency on cellular pathways and phenotype expression, providing deeper insights into the gene’s role in health and disease.
The fundamental function of RNF126 lies in its involvement in regulating protein stability and mediating the cellular response to stress signals. By disrupting this gene, scientists can examine its effects on processes such as cell cycle progression, apoptosis, and response to genomic insults. The resulting cell lines serve as invaluable resources for research focused on cancer biology, neurodegenerative disorders, and metabolic syndromes, where aberrant ubiquitination is often a hallmark.
In clinical and research settings, the RNF126 Gene Knockout Cell Lines are invaluable for elucidating therapeutic targets, developing small-molecule inhibitors, and validating the role of RNF126 in various disease states. Compared to traditional knockout methods, CRISPR-generated cell lines offer increased efficiency, specificity, and ease of generation, significantly accelerating the pace of research while minimizing off-target effects.
Researchers and clinicians seeking reliable models for functional assays will find that these cell lines not only provide an efficient platform for testing hypotheses surrounding RNF126 but also facilitate the exploration of potential drug candidates. Ultimately, the RNF126 Gene Knockout Cell Lines exemplify an innovative leap in biological research tools, enabling experts to push the boundaries of our understanding of gene function and associated pathologies.
With a commitment to advancing research through robust, scientifically validated products, our company stands at the forefront of genetic investigation, offering an extensive range of cell lines and tools designed to empower innovation in the life sciences.
Please note that all services are for research use only. Not intended for any clinical use.
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