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RNF114 Knockout Cell Lines

Gene: RNF114

Official Full Name: ring finger protein 114provided by HGNC

Gene Summary: Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein polyubiquitination and ubiquitin-dependent protein catabolic process. Located in cytosol and plasma membrane. Biomarker of male infertility. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO00220 RNF114 Knockout cell line (MDA-MB-231) Human RNF114 1:2~1:4 Negative Online Inquiry
KO04950 RNF114 Knockout cell line (HeLa) Human RNF114 1:3~1:6 Negative Online Inquiry
KO04951 RNF114 Knockout cell line (HCT 116) Human RNF114 1:2~1:4 Negative Online Inquiry
KO04952 RNF114 Knockout cell line (HEK293) Human RNF114 1:3~1:6 Negative Online Inquiry
KO04953 RNF114 Knockout cell line (A549) Human RNF114 1:3~1:4 Negative Online Inquiry

Background

RNF114 Gene Knockout Cell Lines are genetically modified cellular models designed to study the biological functions and pathways associated with the RNF114 gene. These cell lines are engineered using advanced CRISPR-Cas9 technology to create specific and precise deletions within the genome, effectively disrupting the expression of the RNF114 gene. The key functions of these cell lines include enabling researchers to investigate the role of RNF114 in cellular processes such as ubiquitination, signal transduction, and gene regulation, which are crucial in various physiological and pathological contexts, including cancer and autoimmune diseases.

The scientific importance of RNF114 Gene Knockout Cell Lines lies in their wide-ranging applications in both basic research and clinical settings. By employing these cell lines, scientists can elucidate the pathways that RNF114 regulates and its potential involvement in disease mechanisms, facilitating the identification of therapeutic targets. Furthermore, these models are integral for drug screening and biomarker discovery, as they offer insights into how the absence of RNF114 affects cellular responses to various stimuli or treatments.

Compared to traditional knockdown or overexpression models, RNF114 Gene Knockout Cell Lines provide a more straightforward, durable, and thoroughly validated approach to studying gene function. They allow for a complete loss-of-function analysis, yielding clearer and more interpretable data. Importantly, they are optimized for high-throughput applications, making them suitable for large-scale screening processes.

For researchers and clinicians alike, these cell lines represent a valuable tool for advancing our understanding of RNF114-related biological phenomena. The ability to manipulate the RNF114 gene offers immense potential for unraveling complex cellular interactions and disease states. Our company holds extensive expertise in genetic engineering and cell line development, ensuring that our products maintain the highest quality and reliability standards to meet the rigorous demands of scientific inquiry. With a commitment to innovation and excellence, we empower researchers to explore the frontiers of cellular biology effectively.

Please note that all services are for research use only. Not intended for any clinical use.

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