Gene: RMND5A
Official Full Name: required for meiotic nuclear division 5 homolog Aprovided by HGNC
Gene Summary: Predicted to enable metal ion binding activity and ubiquitin protein ligase activity. Predicted to contribute to ubiquitin-protein transferase activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process and protein polyubiquitination. Located in cytoplasm and nucleoplasm. Part of ubiquitin ligase complex. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO14501 | RMND5A Knockout cell line (HeLa) | Human | RMND5A | 1:3~1:6 | Negative | Online Inquiry |
KO14502 | RMND5A Knockout cell line (HCT 116) | Human | RMND5A | 1:2~1:4 | Negative | Online Inquiry |
KO14503 | RMND5A Knockout cell line (HEK293) | Human | RMND5A | 1:3~1:6 | Negative | Online Inquiry |
KO14504 | RMND5A Knockout cell line (A549) | Human | RMND5A | 1:3~1:4 | Negative | Online Inquiry |
RMND5A Gene Knockout Cell Lines are specialized cell lines engineered to effectively disable the RMND5A gene, which encodes a critical protein involved in various cellular processes, including ribosome biogenesis and mitochondrial function. By utilizing advanced CRISPR/Cas9 gene-editing technology, these cell lines provide researchers with a comprehensive platform to study the functional outcomes of RMND5A deficiency in vitro.
The key mechanism underlying RMND5A knockout involves the targeted disruption of the gene sequence, which leads to the ablation of the gene product. As a result, scientists can investigate the physiological implications of RMND5A loss, including its effects on cellular homeostasis, stress responses, and developmental processes. This is crucial for understanding the role of RMND5A in diseases such as cancer, neurodegenerative disorders, and metabolic syndromes.
Scientifically, the RMND5A Gene Knockout Cell Lines hold significant importance for both basic research and clinical applications. They serve as valuable tools for elucidating the pathways regulated by RMND5A, aiding in the identification of potential therapeutic targets. Moreover, these cell lines can facilitate drug discovery efforts, enabling researchers to screen for compounds that may restore function or counteract the effects of RMND5A loss.
Distinct from conventional cell lines, our RMND5A knockout models offer remarkable specificity and reproducibility, which are essential for obtaining reliable experimental data. These cell lines come with detailed validation data, ensuring that researchers can understand the extent of the gene knockout and its implications on cellular behavior.
For researchers, clinicians, and pharmaceutical companies alike, the RMND5A Gene Knockout Cell Lines represent a breakthrough in the exploration of gene function and disease mechanisms. Our commitment to quality and innovation in biological product development positions us as a leader in the field, providing you with exceptional tools to advance your research and therapeutic initiatives.
Please note that all services are for research use only. Not intended for any clinical use.
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