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RIC8A Knockout Cell Lines

Gene: RIC8A

Official Full Name: RIC8 guanine nucleotide exchange factor Aprovided by HGNC

Gene Summary: Predicted to enable G-protein alpha-subunit binding activity; GTPase regulator activity; and protein folding chaperone. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to act upstream of or within several processes, including basement membrane organization; gastrulation; and visual learning. Predicted to be located in cell cortex; endomembrane system; and membrane. Predicted to be active in cytoplasm and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO14544 RIC8A Knockout cell line (HeLa) Human RIC8A 1:3~1:6 Negative Online Inquiry
KO14545 RIC8A Knockout cell line (HCT 116) Human RIC8A 1:2~1:4 Negative Online Inquiry
KO14546 RIC8A Knockout cell line (HEK293) Human RIC8A 1:3~1:6 Negative Online Inquiry
KO14547 RIC8A Knockout cell line (A549) Human RIC8A 1:3~1:4 Negative Online Inquiry

Background

RIC8A Gene Knockout Cell Lines are a revolutionary tool designed for investigating the physiological roles of the RIC8A gene, a critical component in the regulation of G protein signaling pathways. By employing CRISPR/Cas9 technology, these cell lines provide a precise and efficient method for generating gene knockouts, allowing researchers to explore the implications of RIC8A deficiency in cellular functions and disease models.

The primary function of the RIC8A Gene Knockout Cell Lines is to facilitate the study of the gene's role in G protein-coupled receptor signaling and its downstream effects on various cellular processes, including growth, differentiation, and response to external stimuli. By creating a cellular environment devoid of RIC8A, researchers can decipher the mechanistic pathways involved and elucidate the gene's contributions to complex biological phenomena, such as tumorigenesis or neurodegenerative conditions.

The scientific importance of these cell lines extends to both fundamental research and clinical applications. They serve as a crucial tool for drug discovery and development, enabling scientists to assess the efficacy of potential therapeutics targeting G protein signaling, as well as providing insights into the molecular underpinnings of related diseases. In research labs, these cell lines can be invaluable in validating experimental data and hypotheses regarding RIC8A and its interactions.

Compared to traditional knockout models, RIC8A Gene Knockout Cell Lines offer several advantages: they exhibit less variability, faster turnaround times in generating results, and the ability to be used in high-throughput screening applications. Additionally, the CRISPR/Cas9-mediated approach minimizes off-target effects, ensuring that the outcomes are directly attributable to RIC8A knockout, which boosts the reliability of research findings.

For researchers and clinicians alike, these cell lines represent a unique asset in the quest to unravel complex biological questions and translate findings into clinical solutions. Their robust design and proven efficacy provide confidence in generating reproducible results that can advance both academic and biopharmaceutical pursuits.

Our company's expertise in gene editing technologies and commitment to providing high-quality biological products ensures that RIC8A Gene Knockout Cell Lines meet rigorous scientific standards. We are dedicated to supporting the research community with innovative tools that drive groundbreaking discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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