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RHPN1 Knockout Cell Lines

Gene: RHPN1

Official Full Name: rhophilin Rho GTPase binding protein 1provided by HGNC

Gene Summary: Predicted to be involved in negative regulation of stress fiber assembly. Predicted to act upstream of or within several processes, including focal adhesion assembly; glomerular filtration; and renal albumin absorption. Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO30724 RHPN1 Knockout cell line (HeLa) Human RHPN1 1:3~1:6 Negative Online Inquiry
KO30725 RHPN1 Knockout cell line (HCT 116) Human RHPN1 1:2~1:4 Negative Online Inquiry
KO30726 RHPN1 Knockout cell line (HEK293) Human RHPN1 1:3~1:6 Negative Online Inquiry
KO30727 RHPN1 Knockout cell line (A549) Human RHPN1 1:3~1:4 Negative Online Inquiry

Background

RHPN1 Gene Knockout Cell Lines are specifically engineered cellular models characterized by the targeted disruption of the RHPN1 gene. This gene is implicated in various biological processes, including cell adhesion, cytoskeletal organization, and intracellular signaling pathways. The knockout mechanism uses CRISPR-Cas9 technology, which enables precise gene editing. This allows researchers to investigate the phenotypic consequences of RHPN1 loss, offering valuable insight into its role in cellular function and pathology.

The primary function of these knockout cell lines is to serve as a powerful tool for exploring the biological implications of RHPN1 deficiency. By providing a controlled environment where the expression of this gene is entirely abrogated, scientists can better understand its contribution to diseases, particularly those involving aberrant cell signaling or migration. The ability to create a cellular model that lacks a specific gene opens avenues for functional assays, including drug screening, gene expression profiling, and mechanistic studies.

The scientific importance of RHPN1 Gene Knockout Cell Lines lies in their potential applications in both fundamental and translational research. These cell lines can be utilized in studies examining cancer biology, neurodegenerative disorders, and various developmental processes, paving the way for novel therapeutic strategies. Additionally, using these models can enhance the reproducibility and reliability of experimental results, which is critical in both academic and clinical research settings.

What sets RHPN1 Gene Knockout Cell Lines apart from alternatives is the robustness of the CRISPR-Cas9 mediated knockout, which ensures efficient and consistent gene disruption. Moreover, our product offers customizability, enabling researchers to select compatible host cells, ensuring optimal experimental conditions and results tailored to specific research needs.

Researchers, clinicians, and institutions looking to deliver impactful studies will find RHPN1 Gene Knockout Cell Lines to be an invaluable resource. These cell models provide clear advantages for elucidating the functional roles of genes in health and disease, fostering innovations in biomolecular research. Backed by our comprehensive expertise in gene editing technologies and our commitment to advancing scientific exploration, we are poised to support the scientific community with high-quality, reliable products that drive discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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