Home / RFLNB Knockout Cell Lines

RFLNB Knockout Cell Lines

Gene: RFLNB

Official Full Name: refilin Bprovided by HGNC

Gene Summary: Enables filamin binding activity. Predicted to be involved in several processes, including actin filament bundle organization; negative regulation of bone mineralization involved in bone maturation; and negative regulation of chondrocyte development. Predicted to act upstream of or within actin cytoskeleton organization and epithelial to mesenchymal transition. Predicted to be located in actin cytoskeleton and cytoplasm. Predicted to be active in actin filament bundle. [provided by Alliance of Genome Resources, Apr 2025]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO14584 RFLNB Knockout cell line (HeLa) Human RFLNB 1:3~1:6 Negative Online Inquiry
KO14585 RFLNB Knockout cell line (HCT 116) Human RFLNB 1:2~1:4 Negative Online Inquiry
KO14586 RFLNB Knockout cell line (HEK293) Human RFLNB 1:3~1:6 Negative Online Inquiry
KO14587 RFLNB Knockout cell line (A549) Human RFLNB 1:3~1:4 Negative Online Inquiry

Background

RFLNB Gene Knockout Cell Lines are highly specialized cellular models designed to facilitate the deep study of the RFLNB gene's function in various biological contexts. These cell lines specifically lack the expression of the RFLNB gene, creating an environment that allows researchers to investigate the gene's role in cellular processes such as proliferation, differentiation, and apoptosis. Produced using advanced CRISPR-Cas9 genome-editing technology, these knockout cell lines ensure precise gene targeting, yielding reliable and reproducible experimental outcomes.

The key function of RFLNB Gene Knockout Cell Lines lies in their ability to reveal phenotypic changes and molecular pathways influenced by the RFLNB gene's absence. By creating a homogenous population devoid of RFLNB, researchers can delve into the gene's involvement in cellular signaling cascades, stress responses, and potential contributions to diseases, including cancer and neurodegeneration. This understanding is critical as it can lead to the identification of novel therapeutic targets and biomarkers.

From a scientific standpoint, RFLNB Gene Knockout Cell Lines are invaluable in both basic research and clinical settings. Their application extends to drug screening, genetic interaction studies, and the development of gene therapies, catering to the ever-evolving landscape of molecular medicine. Compared to traditional knockdown methodologies, the complete gene knockout provides a stronger and clearer interpretation of gene function, minimizing the risk of residual protein expression.

The unique selling point of RFLNB Gene Knockout Cell Lines lies in their high specificity and efficiency, paired with the robustness of CRISPR technology, which offers advantages over transgenic models including time efficiency and ethical simplicity. Additionally, their availability from reputable sources guarantees quality and supports reproducibility in experimental settings.

For researchers and clinicians seeking to unlock the complexities of gene function and its implications in health and disease, RFLNB Gene Knockout Cell Lines represent a highly valuable tool. They empower investigations that can lead to significant breakthroughs in translational research and therapeutic development. Our company prides itself on having expertise in producing high-quality biological products, ensuring that researchers have access to the best tools to advance their knowledge and applications in the life sciences.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.