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RETSAT Knockout Cell Lines

Gene: RETSAT

Official Full Name: retinol saturaseprovided by HGNC

Gene Summary: Predicted to enable all-trans-retinol 13,14-reductase activity. Predicted to be involved in retinol metabolic process. Located in membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO14600 RETSAT Knockout cell line (HeLa) Human RETSAT 1:3~1:6 Negative Online Inquiry
KO14601 RETSAT Knockout cell line (HCT 116) Human RETSAT 1:2~1:4 Negative Online Inquiry
KO14602 RETSAT Knockout cell line (HEK293) Human RETSAT 1:3~1:6 Negative Online Inquiry
KO14603 RETSAT Knockout cell line (A549) Human RETSAT 1:3~1:4 Negative Online Inquiry

Background

RETSAT Gene Knockout Cell Lines are meticulously engineered biological resources designed to facilitate the in-depth study of the RETSAT (reduction-sensitive thiol oxidoreductase) gene’s role in cellular functions. These knockout cell lines are developed through advanced CRISPR-Cas9 technology, enabling precise and efficient disruption of the RETSAT gene. By eliminating the expression of this gene, researchers can investigate its contributions to metabolic pathways such as lipid metabolism and redox signaling, elucidating its involvement in various physiological and pathological conditions.

The primary function of the RETSAT Gene Knockout Cell Lines is to serve as an experimental platform for understanding the biological implications of RETSAT deficiency. Their mechanisms allow for rigorous exploration of cellular responses to oxidative stress and metabolic dysregulation, acting as a valuable tool for evaluating therapeutic strategies against diseases linked to lipid disorders and oxidative stress, including cancer and cardiovascular diseases.

In terms of scientific importance, these cell lines are pivotal in research settings, offering insights into metabolic reprogramming and potential biomarkers for disease states. Their application in preclinical studies can lead to the development of novel therapeutic targets, enhancing our understanding of disease mechanisms and helping to drive clinical advancements.

What distinguishes the RETSAT Gene Knockout Cell Lines from alternatives is their high specificity and gene-targeting efficiency, ensuring that research outcomes are reliable and reproducible. While other models may offer general insights, the precise gene knockout empowers researchers to dissect complex pathways with unparalleled clarity.

Value to researchers and clinicians lies in the potential for groundbreaking discoveries these cell lines afford; they are indispensable for those aiming to bridge the gap between fundamental science and translational medicine. By utilizing the RETSAT Gene Knockout Cell Lines, users can contribute to the foundational knowledge that underpins innovative therapeutic approaches.

Our company boasts extensive expertise in genetic engineering and the development of high-quality biological products tailored for cutting-edge research. We are committed to advancing scientific discovery through our state-of-the-art resources and unwavering support to our customers, ensuring they have the tools necessary to succeed in their pursuits.

Please note that all services are for research use only. Not intended for any clinical use.

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