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REM2 Knockout Cell Lines

Gene: REM2

Official Full Name: RRAD and GEM like GTPase 2provided by HGNC

Gene Summary: Predicted to enable GTP binding activity and calcium channel regulator activity. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO23282 REM2 Knockout cell line (HeLa) Human REM2 1:3~1:6 Negative Online Inquiry
KO23283 REM2 Knockout cell line (HEK293) Human REM2 1:3~1:6 Negative Online Inquiry

Background

REM2 Gene Knockout Cell Lines are innovative cellular models designed to facilitate the study of the REM2 gene's role in various biological processes and disease states. These knockout cell lines are engineered to specifically silence the expression of the REM2 gene, allowing researchers to elucidate its function in neuronal signaling, synaptic regulation, and potential implications in neurodegenerative diseases and psychiatric disorders.

The REM2 gene encodes a protein implicated in the modulation of glutamatergic transmission, and its absence can provide critical insights into the pathophysiology of conditions such as Alzheimer’s disease or schizophrenia. By employing CRISPR-Cas9 technology, these cell lines ensure precise gene editing, leading to high efficiency in gene knockout and minimal off-target effects. Researchers can then utilize these models to explore alterations in cellular signaling pathways, assess changes in phenotype, and identify novel therapeutic targets.

The importance of REM2 Gene Knockout Cell Lines extends into both research and clinical settings. In the laboratory, they serve as vital tools for screening drug candidates, understanding gene function in a controlled environment, and conducting high-throughput assays. Clinically, insights gained from these models may accelerate the development of therapeutic strategies aimed at modulating REM2-related pathways, ultimately contributing to more effective treatments for neurodegenerative conditions.

What sets REM2 Gene Knockout Cell Lines apart from alternative models is their specificity combined with the robustness of the technology used in their creation. While traditional knockouts may exhibit variable expression or incomplete gene silencing, our cell lines provide reliable and reproducible models that researchers can depend on. This enhances the validity of experimental outcomes and ensures that researchers are working with the best tools available.

For academics, pharmaceutical companies, and clinical researchers, investing in REM2 Gene Knockout Cell Lines means gaining access to cutting-edge models that drive forward the understanding of complex biological systems. At our company, we pride ourselves on delivering high-quality, innovative biological products backed by comprehensive expertise in genetic engineering and cell line development, ensuring that our customers have the tools they need to achieve breakthroughs in their research endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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