Gene: RBP7
Official Full Name: retinol binding protein 7provided by HGNC
Gene Summary: The protein encoded by this gene is a member of the cellular retinol-binding protein (CRBP) family, whose members are required for vitamin A stability and metabolism. The encoded protein binds all-trans-retinol and is structurally similar to other CRBPs; however, it has a lower binding affinity for retinol than other CRBPs. [provided by RefSeq, Aug 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO30526 | RBP7 Knockout cell line (HCT 116) | Human | RBP7 | 1:2~1:4 | Negative | Online Inquiry |
KO30527 | RBP7 Knockout cell line (HEK293) | Human | RBP7 | 1:3~1:6 | Negative | Online Inquiry |
KO30528 | RBP7 Knockout cell line (A549) | Human | RBP7 | 1:3~1:4 | Negative | Online Inquiry |
RBP7 Gene Knockout Cell Lines represent a significant advancement in the study of gene function and regulation, specifically pertaining to the Retinol Binding Protein 7 (RBP7). These specialized cell lines are designed to facilitate research by eliminating the expression of the RBP7 gene, enabling scientists to elucidate the biological roles and potential pathways associated with this crucial protein. The knockout mechanism employs targeted gene editing techniques, such as CRISPR/Cas9, ensuring precise alteration within the genome, thereby providing a robust platform for various experimental paradigms.
At the core of RBP7's biological function is its role in the transport and metabolism of retinoids, which are vital for numerous physiological processes including vision, cell differentiation, and immune function. By utilizing RBP7 knockout cell lines, researchers can investigate the effects of RBP7 deficiency on cellular processes, signaling pathways, and broader systemic responses, which may have implications in understanding developmental biology, cancer, and degenerative diseases. The scientific importance of these cell lines extends to the development of targeted therapies, wherein detailed insights into RBP7’s functions can guide therapeutic interventions.
Compared to traditional cell lines or wild-type models, RBP7 Gene Knockout Cell Lines offer unique advantages, such as the elimination of confounding variables associated with RBP7 expression, and an innovative model for studying gene function in a controlled environment. Furthermore, these lines provide a reliable framework for high-throughput drug screening and functional genomics studies.
For researchers and clinicians addressing challenges in gene function and therapeutic targets, RBP7 Gene Knockout Cell Lines are invaluable tools that streamline experimental design and enhance the reproducibility of results. Investing in these cell lines not only empowers cutting-edge research but also accelerates the discovery of novel therapeutic strategies.
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