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RBMS3 Knockout Cell Lines

Gene: RBMS3

Official Full Name: RNA binding motif single stranded interacting protein 3provided by HGNC

Gene Summary: This gene encodes an RNA-binding protein that belongs to the c-myc gene single-strand binding protein family. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. The encoded protein was isolated by virtue of its binding to an upstream element of the alpha2(I) collagen promoter. The observation that this protein localizes mostly in the cytoplasm suggests that it may be involved in a cytoplasmic function such as controlling RNA metabolism, rather than transcription. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO27662 RBMS3 Knockout cell line (HeLa) Human RBMS3 1:3~1:6 Negative Online Inquiry
KO27663 RBMS3 Knockout cell line (HEK293) Human RBMS3 1:3~1:6 Negative Online Inquiry
KO27664 RBMS3 Knockout cell line (A549) Human RBMS3 1:3~1:4 Negative Online Inquiry

Background

RBMS3 Gene Knockout Cell Lines are specialized cellular models wherein the RBMS3 gene has been systematically disrupted to understand its biological functions and interactions. RBMS3 (RNA Binding Motif Protein 3) is known to play a critical role in RNA metabolism, cellular proliferation, and differentiation. By providing a means to study the effects of RBMS3 loss in a controlled environment, these knockout cell lines are pivotal for researchers investigating gene regulation, signal transduction pathways, and cellular responses to various stimuli.

The primary function of the RBMS3 Gene Knockout Cell Lines lies in their ability to reveal insights regarding the molecular mechanisms associated with gene silencing and its impact on the cellular life cycle. By utilizing these cell lines, researchers can delve into cellular processes such as apoptosis, cancer progression, and the modulation of gene expression. The absence of RBMS3 allows for a comparative analysis to be conducted with wild-type cells, offering a clear viewpoint on how gene knockout influences cellular activity and contributes to key metabolic pathways.

In scientific research, these knockout cell lines are invaluable tools in elucidating the roles of RBMS3 within both physiological and pathological contexts, particularly in oncology and regenerative medicine. They serve as platforms for high-throughput screening of potential therapeutic agents and help uncover the functional relevance of RNA-binding proteins in disease models.

One of the significant advantages of our RBMS3 Gene Knockout Cell Lines is their rigorous generation and validation process, ensuring consistent performance and reliability. Compared to other cellular models, our lines offer targeted disruption of the RBMS3 gene without off-target effects, thus providing clearer, more definitive findings. This specificity is crucial for researchers seeking to draw accurate conclusions from their experiments.

For researchers and clinicians, investing in RBMS3 Gene Knockout Cell Lines means gaining access to a robust, scientifically validated resource that deepens understanding of gene function and disease mechanisms. This knowledge is crucial for developing innovative therapeutic strategies and advancing the field of molecular biology.

Our company prides itself on a commitment to quality and innovation in producing biological products. Through our expertise in cell line development, we continue to provide researchers with essential tools that power discovery and breakthroughs in understanding complex biological processes.

Please note that all services are for research use only. Not intended for any clinical use.

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