Home / RAB11FIP2 Knockout Cell Lines

RAB11FIP2 Knockout Cell Lines

Gene: RAB11FIP2

Official Full Name: RAB11 family interacting protein 2provided by HGNC

Gene Summary: Enables protein homodimerization activity and protein kinase binding activity. Involved in several processes, including TRAM-dependent toll-like receptor 4 signaling pathway; phagocytosis; and positive regulation of GTPase activity. Located in endosome; nucleoplasm; and phagocytic cup. [provided by Alliance of Genome Resources, Apr 2025]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO30281 RAB11FIP2 Knockout cell line (HeLa) Human RAB11FIP2 1:3~1:6 Negative Online Inquiry
KO30282 RAB11FIP2 Knockout cell line (HCT 116) Human RAB11FIP2 1:2~1:4 Negative Online Inquiry
KO30283 RAB11FIP2 Knockout cell line (HEK293) Human RAB11FIP2 1:3~1:6 Negative Online Inquiry
KO30284 RAB11FIP2 Knockout cell line (A549) Human RAB11FIP2 1:3~1:4 Negative Online Inquiry

Background

RAB11FIP2 Gene Knockout Cell Lines are specialized cellular models that have been engineered to lack the RAB11 family interacting protein 2 (RAB11FIP2), a crucial regulator involved in the recycling endosome pathway. These cell lines serve as a powerful tool for researchers to investigate the roles of RAB11FIP2 in intracellular transport processes and its broader implications in cellular signaling and metastasis. The knockout mechanism is achieved through CRISPR/Cas9 technology, ensuring precise gene disruption while minimizing off-target effects.

The primary function of RAB11FIP2 involves its interaction with the RAB11 GTPase, which plays a pivotal role in sorting and trafficking endosomal cargo to the recycling pathway. By employing these gene knockout cell lines, researchers can elucidate the functional significance of RAB11FIP2 in various biological processes, including cellular adhesion, migration, and vesicle trafficking. Understanding these mechanisms is essential for uncovering the molecular underpinnings behind diseases such as cancer, where dysregulated endosomal sorting can contribute to invasive properties.

The scientific importance of RAB11FIP2 Gene Knockout Cell Lines extends beyond basic research. Their application in clinical models has shown potential in cancer research, offering insights into targeted therapies that could inhibit tumor progression. Compared to traditional models, these knockout cell lines provide a more accurate representation of the genetic landscape in specific pathological contexts, allowing for better translation of research findings to clinical outcomes.

One of the key advantages of adopting RAB11FIP2 Gene Knockout Cell Lines is their specificity; researchers can observe the targeted effects of RAB11FIP2 absence without the confounding influences associated with alternative methods. This specificity enhances experimental reproducibility and reliability, making them an invaluable resource for scientists seeking to delve deeper into the complexities of cellular dynamics.

Investing in RAB11FIP2 Gene Knockout Cell Lines not only equips researchers and clinicians with a cutting-edge tool for innovative studies but also underscores our commitment to advancing scientific knowledge. Our company, with extensive expertise in genetic engineering and cell line development, is dedicated to providing researchers with high-quality, reliable biological products that facilitate groundbreaking discoveries in molecular biology and disease research.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.