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PXDN Knockout Cell Lines

Gene: PXDN

Official Full Name: peroxidasinprovided by HGNC

Gene Summary: This gene encodes a heme-containing peroxidase that is secreted into the extracellular matrix. It is involved in extracellular matrix formation, and may function in the physiological and pathological fibrogenic response in fibrotic kidney. Mutations in this gene cause corneal opacification and other ocular anomalies, and also microphthalmia and anterior segment dysgenesis. [provided by RefSeq, Aug 2014]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO03843 PXDN Knockout cell line (HeLa) Human PXDN 1:3~1:6 Negative Online Inquiry
KO03844 PXDN Knockout cell line (HCT 116) Human PXDN 1:2~1:4 Negative Online Inquiry
KO03845 PXDN Knockout cell line (HEK293) Human PXDN 1:3~1:6 Negative Online Inquiry
KO03846 PXDN Knockout cell line (A549) Human PXDN 1:3~1:4 Negative Online Inquiry

Background

PXDN Gene Knockout Cell Lines are specifically engineered cellular models designed to facilitate the investigation of the peroxidase domain containing protein PXDN (peroxidase 2), which plays a crucial role in various biological processes, including oxidative stress responses and extracellular matrix remodeling. These knockout cell lines are created using advanced CRISPR-Cas9 technology to disrupt the PXDN gene, effectively abolishing its normal function. This precise modification allows researchers to study the specific biological impacts of PXDN loss, including alterations in cellular signaling pathways and potential contributions to diseases such as cancer, cardiovascular disorders, and fibrosis.

The primary function of PXDN Gene Knockout Cell Lines is to provide a robust platform to explore gene function and regulation in a controlled environment. By utilizing these cell lines, researchers can perform functional assays to elucidate PXDN's role in key cellular processes and identify downstream effects on cellular behavior. Such insights are invaluable in both basic and applied research, allowing for a deeper understanding of pathological mechanisms and the potential identification of therapeutic targets.

In the clinical research context, these knockout models serve as vital tools for drug discovery and development, enabling scientists to screen for novel compounds that may modulate PXDN-related pathways. Unlike conventional models, which may not accurately mimic human disease states, PXDN Gene Knockout Cell Lines offer a more physiologically relevant approach, thus enhancing the translational value of research findings.

One of the standout advantages of our PXDN Gene Knockout Cell Lines is their high specificity and reliability, derived from rigorous validation processes that confirm the extent of PXDN gene disruption. Additionally, these cell lines are compatible with various applications, including gene expression analysis, physiology studies, and therapeutic response evaluations, making them a versatile choice for laboratories.

For researchers and clinicians looking to deepen their understanding of PXDN's role in health and disease, investing in PXDN Gene Knockout Cell Lines is invaluable. They not only streamline experimental protocols but also pave the way for breakthroughs in therapeutic strategies. Our company is committed to advancing the field of cellular biology by offering precise, high-quality biological products backed by years of expertise and innovative research practices.

Please note that all services are for research use only. Not intended for any clinical use.

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